Results 111 to 120 of about 23,206 (306)
Advanced Healthcare Materials, EarlyView.Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang +14 more
wiley +1 more source
Understanding the molecular basis of the strength differences in skins used in leather manufacture : a dissertation presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Massey University, Palmerston North, New Zealand [PDF]
, 2017 Although skin structure and its physical properties have been extensively studied, little research has been devoted to understanding the links between them.
Naffa, Rafea Mustafa
core
The gentle grip of a helping hand [PDF]
, 2015 Using NMR spectroscopy, Zhao and colleagues, in this issue, have modeled the short-lived complex formed between the MT1-MMP hemopexin domain and a synthetic triple-helical collagen mimetic.
Pickford, Andy
core +2 more sources
Advanced Healthcare Materials, EarlyView.Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu +8 more
wiley +1 more source
Mechanical forces regulate the interactions of fibronectin and collagen I in extracellular matrix [PDF]
, 2015 Despite the crucial role of extracellular matrix (ECM) in directing cell fate in healthy and diseased tissues--particularly in development, wound healing, tissue regeneration and cancer--the mechanisms that direct the assembly and regulate hierarchical ...
Gourdon, Delphine +7 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan +8 more
wiley +1 more source
Mechanical model for a collagen fibril pair in extracellular matrix [PDF]
arXiv, 2009 In this paper, we model the mechanics of a collagen pair in the connective tissue extracellular matrix that exists in abundance throughout animals, including the human body. This connective tissue comprises repeated units of two main structures, namely collagens as well as axial, parallel and regular anionic glycosaminoglycan between collagens.
arxiv
In silico modeling of the rheological properties of covalently crosslinked collagen triple helices [PDF]
, 2016 Biomimetic hydrogels based on natural polymers are a promising class of biomaterial, mimicking the natural extra-cellular matrix of biological tissues and providing cues for cell attachment, proliferation and differentiation. With a view to providing an upstream method to guide subsequent experimental design, the aim of this study was to introduce a ...
arxiv +1 more source
Fibril-forming collagens in lamprey.
Journal of Biological Chemistry, 1988 Five types of collagen with triple-helical regions approximately 300 nm in length were found in lamprey tissues which show characteristic D-periodic collagen fibrils. These collagens are members of the fibril forming family of this primitive vertebrate.
Shizuko Tanaka +4 more
openaire +3 more sources
Remodeling by fibroblasts alters the rate-dependent mechanical properties of collagen [PDF]
, 2016 The ways that fibroblasts remodel their environment are central to wound healing, development of musculoskeletal tissues, and progression of pathologies such as fibrosis.
Babaei, B. +6 more
core +1 more source