Results 141 to 150 of about 23,206 (306)

Ultra‐Fine 3D Bioprinting of Dynamic Hyaluronic Acid Hydrogel for in Vitro Modeling

open access: yesAdvanced Materials, EarlyView.
3D bioprinting merges tissue engineering and additive manufacturing to create biological structures. A bioink is developed by modifying hyaluronic acid, a natural extracellular matrix polymer, with cysteine. Potassium iodide is later added to tune gelation kinetics, enabling fine printing with a 32G needle.
Shima Tavakoli   +3 more
wiley   +1 more source

Modeling collagen fibril degradation as a function of matrix microarchitecture [PDF]

open access: yesarXiv
Collagenolytic degradation is a process fundamental to tissue remodeling. The microarchitecture of collagen fibril networks changes during development, aging, and disease. Such changes to microarchitecture are often accompanied by changes in matrix degradability.
arxiv  

Crack Propagation in Bone on the Scale of Mineralized Collagen Fibrils : Role of Polymers with Sacrificial Bonds and Hidden Length [PDF]

open access: yesarXiv, 2014
Sacrificial bonds and hidden length (SBHL) in structural molecules provide a mechanism for energy dissipation at the nanoscale. It is hypothesized that their presence leads to greater fracture toughness than what is observed in materials without such features.
arxiv  

Bioxolography Using Diphenyliodonium Chloride and N‐Vinylpyrrolidone Enables Rapid High‐Resolution Volumetric 3D Printing of Spatially Encoded Living Matter

open access: yesAdvanced Materials, EarlyView.
Bioxolography, a novel volumetric 3D‐bioprinting technique, enables rapid and high‐resolution fabrication of >1 cm3 engineered living materials. A newly developed three‐component photoinitiator system significantly enhances the photoreactivity of gelatin methacryloyl‐based bioresins, allowing for precise xolographic bioprinting.
Alexis Wolfel   +6 more
wiley   +1 more source

Hemodynamics Modify Collagen Deposition in the Early Embryonic Chicken Heart Outflow Tract

open access: yesJournal of Cardiovascular Development and Disease, 2017
Blood flow is critical for normal cardiac development. Hemodynamic stimuli outside of normal ranges can lead to overt cardiac defects, but how early heart tissue remodels in response to altered hemodynamics is poorly understood.
Monique Y. Rennie   +5 more
doaj   +1 more source

Intravasation‐On‐µDevice (INVADE): Engineering Dynamic Vascular Interfaces to Study Cancer Cell Intravasation

open access: yesAdvanced Materials, EarlyView.
Cancer metastasis begins with intravasation, a complex process involving cancer‐endothelial interactions. INVADE (Intravasation‐on‐µDevice), a biomimetic microfluidic platform enables high‐throughput analysis of intravasation under controlled conditions.
Fengtao Jiang   +12 more
wiley   +1 more source

Investigating cartilage-related diseases by polarization-resolved second harmonic generation (P-SHG) imaging

open access: yesAPL Bioengineering
Establishing quantitative parameters for differentiating between healthy and diseased cartilage tissues by examining collagen fibril degradation patterns facilitates the understanding of tissue characteristics during disease progression.
Kausalya Neelavara Makkithaya   +12 more
doaj   +1 more source

Biochemical changes in bone in a model of weightlessness [PDF]

open access: yes
The amounts of nonmineralized and mineralized collagen in bone from control, immobilized, and immobilized reambulated monkeys were examined. In order to understand structure function relationships of bone collagen and the reponse of a variety of ...
Mechanic, Gerald L.
core   +1 more source

Microfluidic Production of Ultrathin, Handleable Collagen Sheets Exhibiting Toe‐heel Tensile Behavior

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a microfluidic wet spinning technique for producing ultrathin, templated collagen sheets with hierarchical organization at the microscale. The aligned collagen sheets replicate strain‐stiffening behavior associated with native cardiovascular tissues, sup cell attachment and contraction, and enable biofabrication of load‐bearing ...
Yuming Zhang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy