Results 201 to 210 of about 23,427 (258)

Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation

Advanced Science, EarlyView.
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun, Long Zhao, Zhen Shi, Jingting Wang, Shang Yang, Xia Qi, Hengrui Zhang, Ting Wang, Weiyun Shi   +8 more
wiley   +1 more source

Tensile Mechanical Properties of Isolated Collagen Fibrils Obtained by Microelectromechanical Systems Technology

, 2010
Zhilei Liu Shen
openalex   +1 more source

AI‐Directed 3D Printing of Hierarchical Polyurethane Foams

Advanced Science, EarlyView.
Digitally guided direct ink writing, combined with AI‐generated design, enables the fabrication of hierarchical polyurethane foams with tunable multiscale porosity. This approach produces architected foams featuring interconnected open‐cell networks and tailored mechanical properties, advancing the development of adaptive, high‐performance materials ...
Dhanush Patil, Jie Tian, Kun Jiang, Clarissa Westover, Sri Vaishnavi Thummalapalli, Arunachalam Ramanathan, Arpita Shome, Natalie Crutchfield, M. Taylor Sobczak, Sean Lee, Hongyue Sun, Elizabeth J. Brisbois, Hitesh Handa, Timothy E. Long, Xianqiao Wang, Kenan Song   +15 more
wiley   +1 more source

A 3D Model of the Effect of Tortuosity and Constrictivity on the Diffusion in Mineralized Collagen Fibril. [PDF]

Sci Rep, 2019
Bini F, Pica A, Marinozzi A, Marinozzi F.   +3 more
europepmc   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Modeling the effect of collagen fibril alignment on ligament mechanical behavior. [PDF]

Biomech Model Mechanobiol, 2018
Stender CJ, Rust E, Martin PT, Neumann EE, Brown RJ, Lujan TJ.   +5 more
europepmc   +1 more source

Mechanical properties of mandibular and maxillary bone collagen fibrils based on nonlocal elasticity theory

Elaheh Alibeigi, Alireza Shahidi, B Ebadian   +2 more
openalex   +1 more source

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Combining tensile testing and structural analysis at the single collagen fibril level. [PDF]

Sci Data, 2018
Quigley AS, Bancelin S, Deska-Gauthier D, Légaré F, Veres SP, Kreplak L.   +5 more
europepmc   +1 more source

Collagen Fibril Intermolecular Spacing Changes with 2-Propanol: A Mechanism for Tissue Stiffness

, 2017
Hannah C. Wells, Katie H. Sizeland, S. J. Kelly, Nigel Kirby, Adrian Hawley, Stephen Mudie, R. Haverkamp   +6 more
openalex   +1 more source