3D Raman mapping of the collagen fibril orientation in human osteonal lamellae [PDF]
, 2014 Chemical composition and fibrillar organization are the major determinants of osteonal bone mechanics. However, prominent methodologies commonly applied to investigate mechanical properties of bone on the micro scale are usually not able to concurrently ...
Galvis, L. +4 more
core +2 more sources
Unraveling capillary interaction and viscoelastic response in atomic force microscopy of hydrated collagen fibrils [PDF]
Nanoscale 9 (2017) 1244-1256, 2019 The mechanical properties of collagen fibrils depend on the amount and the distribution of water molecules within the fibrils. Here, we use atomic force microscopy (AFM) to study the effect of hydration on the viscoelastic properties of reconstituted type I collagen fibrils in air with controlled relative humidity. With the same AFM tip, we investigate
arxiv +1 more source
Phase-field collagen fibrils: Coupling chirality and density modulations [PDF]
Phys. Rev. Research 2, 012070 (2020), 2020 To describe the interaction between longitudinal density modulations along collagen fibrils (the D-band) with the radial twist-field of molecular orientation (double-twist), we couple phase-field-crystal (PFC) with liquid-crystalline free-energies to obtain a hybrid model of equilibrium collagen fibril structure.
arxiv +1 more source
Biosensors and Bioelectronics: X, 2022 The detection of collagen fibrils and fibrillation is crucial for tissue regeneration, biomedical applications of collagen, and for studying the interaction of small molecules with the collagen fibrils in the development of therapeutics for collagen ...
Smriti Mukherjee +3 more
doaj
Soluble silicon patterns and templates: calcium phosphate nanocrystal deposition in collagen type 1 [PDF]
, 2016 Patterned mineralisation is a feature of many hard-tissues. The impressive mechanical properties exhibited by such tissues can be, in part, attributed to the patterned deposition of mineral within the organic matrix.
Birdi-Chouhan, G. +8 more
core +2 more sources
Measurement of Elastic Modulus of Collagen Type I Single Fiber. [PDF]
PLoS ONE, 2016 Collagen fibers are the main components of the extra cellular matrix and the primary contributors to the mechanical properties of tissues. Here we report a novel approach to measure the longitudinal component of the elastic moduli of biological fibers ...
Pavel Dutov +4 more
doaj +1 more source
Contribution of postnatal collagen reorientation to depth-dependent mechanical properties of articular cartilage [PDF]
The collagen fibril network is an important factor for the depth-dependent mechanical behaviour of adult articular cartilage (AC). Recent studies show that collagen orientation is parallel to the articular surface throughout the tissue depth in perinatal
Kranenbarg, S. +2 more
core +2 more sources
Matrix stiffness and architecture drive fibro-adipogenic progenitors’ activation into myofibroblasts
Scientific Reports, 2022 Fibro-adipogenic progenitors (FAPs) are essential in supporting regeneration in skeletal muscle, but in muscle pathologies FAPs the are main source of excess extracellular matrix (ECM) resulting in fibrosis.
Taryn Loomis +5 more
doaj +1 more source
Tendon proper- and peritenon-derived progenitor cells have unique tenogenic properties. [PDF]
, 2014 IntroductionMultipotent progenitor populations exist within the tendon proper and peritenon of the Achilles tendon. Progenitor populations derived from the tendon proper and peritenon are enriched with distinct cell types that are distinguished by ...
Adams, Sheila M +2 more
core +1 more source
Mathematical modeling of collagen turnover in biological tissue [PDF]
, 2012 The final publication is available at Springer via http://dx.doi.org/10.1007/s00285-012-0613-yWe present a theoretical and computational model for collagen turnover in soft biological tissues. Driven by alterations in the mechanical environment, collagen
Kuhl, Ellen +3 more
core +2 more sources