Results 71 to 80 of about 23,206 (306)

Kinetic model description of dissipation and recovery in collagen fibrils under cyclic loading [PDF]

arXiv, 2022
Collagen fibrils, when subjected to cyclic loading, are known to exhibit hysteretic behaviour with energy dissipation that is partially recovered on relaxation. In this paper, we develop a kinetic model for a collagen fibril incorporating presence of hidden loops and stochastic fragmentation as well as reformation of sacrificial bonds. We show that the
arxiv  

On the tear resistance of skin. [PDF]

, 2015
Tear resistance is of vital importance in the various functions of skin, especially protection from predatorial attack. Here, we mechanistically quantify the extreme tear resistance of skin and identify the underlying structural features, which lead to ...
Gludovatz, Bernd, Meyers, Marc A, Ritchie, Robert O, Schaible, Eric, Sherman, Vincent R, Stewart, Polite, Yang, Wen   +6 more
core   +2 more sources

Direct Ink Writing of Conductive Hydrogels

Advanced Functional Materials, EarlyView.
This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho, Aline Braz Ramirez, Negar Akbarnia, Eric Croiset, Elisabeth Prince, Gerald G. Fuller, Milad Kamkar   +6 more
wiley   +1 more source

Collagen Structure-Function Mapping Informs Applications for Regenerative Medicine

Bioengineering, 2020
Type I collagen, the predominant protein of vertebrates, assembles into fibrils that orchestrate the form and function of bone, tendon, skin, and other tissues.
James D. San Antonio, Olena Jacenko, Andrzej Fertala, Joseph P.R.O. Orgel   +3 more
doaj   +1 more source

Development of a facile method to compute collagen network pathological anisotropy using AFM imaging

Scientific Reports, 2023
Type I collagen, a fundamental extracellular matrix (ECM) component, is pivotal in maintaining tissue integrity and strength. It is also the most prevalent fibrous biopolymer within the ECM, ubiquitous in mammalian organisms.
Emilie Khattignavong, Mehrnoosh Neshatian, Mina Vaez, Amaury Guillermin, Josephine T. Tauer, Marianne Odlyha, Nimish Mittal, Svetlana V. Komarova, Hassan Zahouani, Laurent Bozec   +9 more
doaj   +1 more source

Thermal (in)stability of type I collagen fibrils [PDF]

, 2008
We measured Young's modulus at temperatures ranging from 20 to 100 ^{\circ}$C for a collagen fibril taken from rat's tendon. The hydration change under heating and the damping decrement were measured as well. At physiological temperatures $25-45^{\circ}$C Young's modulus decreases, which can be interpreted as instability of collagen.
arxiv   +1 more source

Dissipation and recovery in collagen fibrils under cyclic loading: a molecular dynamics study [PDF]

arXiv, 2023
The hysteretic behavior exhibited by collagen fibrils, when subjected to cyclic loading, is known to result in both dissipation as well as accumulation of residual strain. On subsequent relaxation, partial recovery has also been reported. Cross-links have been considered to play a key role in overall mechanical properties.
arxiv  

Mechanical Competence and Bone Quality Develop During Skeletal Growth. [PDF]

, 2019
Bone fracture risk is influenced by bone quality, which encompasses bone's composition as well as its multiscale organization and architecture. Aging and disease deteriorate bone quality, leading to reduced mechanical properties and higher fracture ...
Amling, Michael, Busse, Björn, Chushkin, Yuriy, Gludovatz, Bernd, Püschel, Klaus, Riedel, Christoph, Ritchie, Robert O, Schaible, Eric, Schmidt, Felix N, Stockhausen, Kilian E, Vettorazzi, Eik, Zimmermann, Elizabeth A, Zontone, Federico   +12 more
core   +1 more source

Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine

Advanced Functional Materials, EarlyView.
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang, Xin Zhang, Denghui Xie, Chunying Chen, Zhifeng Huang, Zhong Alan Li   +5 more
wiley   +1 more source

Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

eLife
Collagen-I fibrillogenesis is crucial to health and development, where dysregulation is a hallmark of fibroproliferative diseases. Here, we show that collagen-I fibril assembly required a functional endocytic system that recycles collagen-I to assemble ...
Joan Chang, Adam Pickard, Jeremy A Herrera, Sarah O'Keefe, Richa Garva, Matthew Hartshorn, Anna Hoyle, Lewis Dingle, John Knox, Thomas A Jowitt, Madeleine Coy, Jason Wong, Adam Reid, Yinhui Lu, Cédric Zeltz, Rajamiyer V Venkateswaran, Patrick T Caswell, Stephen High, Donald Gullberg, Karl E Kadler   +19 more
doaj   +1 more source