Results 1 to 10 of about 387,585 (164)
Current Insights into Collagen Type I [PDF]
Polymers, 2021 Collagen type I (Col-I) is unique due to its high biocompatibility in human tissue. Despite its availability from various sources, Col-I naturally mimics the extracellular matrix (ECM) and generally makes up the larger protein component (90%) in vasculature, skin, tendon bone, and other tissue.
Ruth Naomi +2 more
openaire +3 more sources
A Comprehensive Review on Collagen Type I Development of Biomaterials for Tissue Engineering: From Biosynthesis to Bioscaffold [PDF]
Biomedicines, 2022 Collagen is the most abundant structural protein found in humans and mammals, particularly in the extracellular matrix (ECM). Its primary function is to hold the body together.
Ibrahim N. Amirrah +5 more
doaj +2 more sources
Elevated ITGA2 expression promotes collagen type I-induced clonogenic growth of intrahepatic cholangiocarcinoma [PDF]
Scientific Reports, 2022 Intrahepatic cholangiocarcinoma (iCCA) arises along the peripheral bile ducts and is often accompanied by a tumor microenvironment (TME) high in extracellular matrices (ECMs).
Chotirat Rattanasinchai +2 more
doaj +2 more sources
Two Distinct Mechanisms Underlying γδ T Cell-Mediated Regulation of Collagen Type I in Lung Fibroblasts [PDF]
Cells, 2022 Idiopathic pulmonary fibrosis is a chronic intractable lung disease, leading to respiratory failure and death. Although anti-fibrotic agents delay disease progression, they are not considered curative treatments, and alternative modalities have attracted
Daisuke Okuno +11 more
doaj +2 more sources
Elevated serum levels of anti-collagen type I antibodies in patients with spontaneous cervical artery dissection and ischemic stroke: a prospective multicenter study [PDF]
Frontiers in ImmunologyIntroductionSpontaneous cervical artery dissection (sCAD) is a rare vasculopathy whose trigger is still unknown. We hypothesized that autoimmunity against components of the vascular wall might play a critical role in sCAD and examined anti-collagen type ...
Silke Zimmermann +7 more
doaj +2 more sources
Morphometric analysis of the human endoneurial extracellular matrix components during aging [PDF]
Archives of Biological Sciences, 2021 The aim of this study was to analyze the expression of extracellular matrix (ECM) proteins in human endoneurium during aging. We harvested 15 cadaveric sural nerves, distributed in 3 age groups (I: 25-44, II: 45-64, III: 65-86 years old).
Kundalić Braca K. +8 more
doaj +1 more source
Streptococcus mutans Proteases Degrade Dentinal Collagen
Dentistry Journal, 2022 Here, we explored the role of S. mutans’s whole cell and discrete fractions in the degradation of type I collagen and dentinal collagen. Type I collagen gels and human demineralized dentin slabs (DS) were incubated in media alone or with one of the ...
Bo Huang +5 more
doaj +1 more source
Biomedicines, 2023 The aim of this study was to investigate the relationship between the collagen type I/III ratio and scarring in patients who underwent immediate reconstruction with the round block technique (RBT) after breast conservation surgery. Seventy-eight patients
Hyo-young Kim +7 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Collagen has grown increasingly present in bioprinting, however collagen bioprinting has mostly been limited to the extrusion printing of collagen type I to form weak collagen hydrogels.
Rory Gibney +2 more
doaj +1 more source
Acta Biochimica et Biophysica Sinica, 2022 Aberrant deposition of collagen is associated with cancer development and tissue fibrosis. Proline hydroxylation, catalyzed by collagen prolyl 4-hydroxylases (C-P4Hs), is necessary for collagen maturation and secretion.
Shi Run +6 more
doaj +1 more source