Results 11 to 20 of about 646,289 (307)
Acta Biochimica et Biophysica Sinica, 2022 Aberrant deposition of collagen is associated with cancer development and tissue fibrosis. Proline hydroxylation, catalyzed by collagen prolyl 4-hydroxylases (C-P4Hs), is necessary for collagen maturation and secretion.
Shi Run +6 more
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Nanomechanics of Type I Collagen [PDF]
Biophysical Journal, 2016 Type I collagen is the predominant collagen in mature tendons and ligaments, where it gives them their load-bearing mechanical properties. Fibrils of type I collagen are formed by the packing of polypeptide triple helices. Higher-order structures like fibril bundles and fibers are assembled from fibrils in the presence of other collagenous molecules ...
Sameer, Varma +2 more
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Animals, 2023 Intramuscular connective tissue (IMCT) collagen is an important factor in meat quality. This study analyzed the characteristics of type I and III collagen in the IMCT of the semitendinosus (SD) and longissimus dorsi (LD) of Wuzhumuqin sheep at different ...
Xige He +9 more
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Collagen fibril formation in vitro: From origin to opportunities
Materials Today Bio, 2022 Sometimes, to move forward, it is necessary to look back. Collagen type I is one of the most commonly used biomaterials in tissue engineering and regenerative medicine.
Diana M. Darvish
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Toxins, 2023 Consumption coagulopathy and hemorrhagic syndrome exacerbated by blood anticoagulability remain the most important causes of lethality associated with Bothrops snake envenomation.
Olivier Pierre-Louis +7 more
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Altered collagen I and premature pulmonary embryonic differentiation in patients with OI type II
Physiological Reports, 2023 Pulmonary hypoplasia and respiratory failure are primary causes of death in patients with osteogenesis imperfecta (OI) type II. OI is a genetic skeletal disorder caused by pathogenic variants in genes encoding collagen type I.
S. Storoni +9 more
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Biochemical markers of bone collagen type I metabolism [PDF]
The Ukrainian Biochemical Journal, 2015 This review focuses on the analysis of diagnostic value of the major bone remodeling markers, in particular synthesis and degradation markers of collagen type I.
O. V. Zaitseva +2 more
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Live Imaging of Type I Collagen Assembly Dynamics in Osteoblasts Stably Expressing GFP and mCherry-Tagged Collagen Constructs [PDF]
, 2018 Type I collagen is the most abundant extracellular matrix protein in bone and other connective tissues and plays key roles in normal and pathological bone formation as well as in connective tissue disorders and fibrosis.
Bonewald, Lynda F. +9 more
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Interaction of Biglycan with Type I Collagen [PDF]
Journal of Biological Chemistry, 1995 The small proteoglycan decorin is known to interact with type I collagen fibrils, thereby influencing the kinetics of fibril formation and the distance between adjacent collagen fibrils. The structurally related proteoglycan biglycan has been proposed not to bind to fibrillar collagens.
E, Schönherr +5 more
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Lung collagens perpetuate pulmonary fibrosis via CD204 and M2 macrophage activation. [PDF]
PLoS ONE, 2013 Idiopathic pulmonary fibrosis is characterized by abundant collagen production and accumulation of alternatively activated macrophages (M2) in the lower respiratory tract.
Mirjam Stahl +6 more
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