Results 11 to 20 of about 5,562 (218)

Increased Binding of von Willebrand Factor to Sub-Endothelial Collagen May Facilitate Thrombotic Events Complicating Bothrops lanceolatus Envenomation in Humans

open access: yesToxins, 2023
Consumption coagulopathy and hemorrhagic syndrome exacerbated by blood anticoagulability remain the most important causes of lethality associated with Bothrops snake envenomation.
Olivier Pierre-Louis   +7 more
doaj   +1 more source

Altered collagen I and premature pulmonary embryonic differentiation in patients with OI type II

open access: yesPhysiological Reports, 2023
Pulmonary hypoplasia and respiratory failure are primary causes of death in patients with osteogenesis imperfecta (OI) type II. OI is a genetic skeletal disorder caused by pathogenic variants in genes encoding collagen type I.
S. Storoni   +9 more
doaj   +1 more source

Biochemical markers of bone collagen type I metabolism [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2015
This review focuses on the analysis of diagnostic value of the major bone remodeling markers, in particular synthesis and degradation markers of collagen type I.
O. V. Zaitseva   +2 more
doaj   +1 more source

Interaction of Biglycan with Type I Collagen [PDF]

open access: yesJournal of Biological Chemistry, 1995
The small proteoglycan decorin is known to interact with type I collagen fibrils, thereby influencing the kinetics of fibril formation and the distance between adjacent collagen fibrils. The structurally related proteoglycan biglycan has been proposed not to bind to fibrillar collagens.
E, Schönherr   +5 more
openaire   +2 more sources

Elevated ITGA2 expression promotes collagen type I-induced clonogenic growth of intrahepatic cholangiocarcinoma

open access: yesScientific Reports, 2022
Intrahepatic cholangiocarcinoma (iCCA) arises along the peripheral bile ducts and is often accompanied by a tumor microenvironment (TME) high in extracellular matrices (ECMs).
Chotirat Rattanasinchai   +2 more
doaj   +1 more source

Lung collagens perpetuate pulmonary fibrosis via CD204 and M2 macrophage activation. [PDF]

open access: yesPLoS ONE, 2013
Idiopathic pulmonary fibrosis is characterized by abundant collagen production and accumulation of alternatively activated macrophages (M2) in the lower respiratory tract.
Mirjam Stahl   +6 more
doaj   +1 more source

Two Distinct Mechanisms Underlying γδ T Cell-Mediated Regulation of Collagen Type I in Lung Fibroblasts

open access: yesCells, 2022
Idiopathic pulmonary fibrosis is a chronic intractable lung disease, leading to respiratory failure and death. Although anti-fibrotic agents delay disease progression, they are not considered curative treatments, and alternative modalities have attracted
Daisuke Okuno   +11 more
doaj   +1 more source

BEVACIZUMAB EFFECT ON EXPRESSION OF COLLAGEN TYPE I AFTER TRABECULECTOMY

open access: yesJournal of Stem Cell Research and Tissue Engineering, 2022
Objective to determine the effect of bevacizumab as an antifibrotic agent on collagen density, collagen thickness and collagen type I after trabeculectomy in rabbit.
Shinta Shinta Arta Wiguna
doaj   +1 more source

Mineralization of Type I Collagen [PDF]

open access: yesBiophysical Journal, 2003
It was previously found that the lateral spacing of the collagen molecules in wet mineralized tissues is exactly proportional to the inverse wet density. Several properties were investigated and the same type of relationship was observed each time. A possible explanation is offered.
openaire   +2 more sources

Clinical significance and biological role of cancer‐derived Type I collagen in lung and esophageal cancers

open access: yesThoracic Cancer, 2019
Background Extracellular matrix (ECM) is remodeled during carcinogenesis. An abundant constituent of ECM is collagen. Type I collagen is secreted by fibroblasts, is important for tumor growth and epithelial‐mesenchymal transition, and may also be ...
Shuo Fang   +7 more
doaj   +1 more source

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