Results 191 to 200 of about 646,289 (307)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Review of collagen type I-based hydrogels: focus on composition-structure-properties relationships. [PDF]

NPJ Biomed Innov
Pires Figueiredo M, Rodríguez-Fernández S, Copes F, Mantovani D.   +3 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Suitability of Marine- and Porcine-Derived Collagen Type I Hydrogels for Bioprinting and Tissue Engineering Scaffolds. [PDF]

Mar Drugs, 2022
Maher M, Glattauer V, Onofrillo C, Duchi S, Yue Z, Hughes TC, Ramshaw JAM, Wallace GG.   +7 more
europepmc   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Discoidin Domain Receptor 2 Contributes to Breast Cancer Progression and Chemoresistance by Interacting with Collagen Type I. [PDF]

Cancers (Basel)
Sato A, Takagi K, Yoshida M, Yamaguchi-Tanaka M, Sagehashi M, Miki Y, Miyashita M, Suzuki T.   +7 more
europepmc   +1 more source

Clinical Significances of Anti-Collagen Type I and Type III Antibodies in Antibody-Mediated Rejection. [PDF]

Transpl Int, 2022
Park S, Yang SH, Kim J, Cho S, Yang J, Min SI, Ha J, Jeong CW, Bhoo SH, Kim YC, Kim DK, Oh KH, Joo KW, Kim YS, Moon KC, Song EY, Lee H.   +16 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

In Vitro Characterization of Human Cell Sources in Collagen Type I Gel Scaffold for Meniscus Tissue Engineering. [PDF]

Gels
Canciani B, Rossi N, Arrigoni E, Giorgino R, Sergio M, Aidos L, Di Giancamillo M, Herrera Millar VR, Peretti GM, Di Giancamillo A, Mangiavini L.   +10 more
europepmc   +1 more source

5-Aza-2'-Deoxycytidine (5-Aza-dC, Decitabine) Inhibits Collagen Type I and III Expression in TGF-β1-Treated Equine Endometrial Fibroblasts. [PDF]

Animals (Basel), 2023
Alpoim-Moreira J, Szóstek-Mioduchowska A, Słyszewska M, Rebordão MR, Skarzynski DJ, Ferreira-Dias G.   +5 more
europepmc   +1 more source