Results 201 to 210 of about 646,289 (307)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Induced collagen type-I secretion by hepatocytes of the melanoma liver metastasis is associated with a reduction in tumour-infiltrating lymphocytes. [PDF]

Clin Transl Med
Mizuno S, Bustos MA, Hayashi Y, Abe K, Furuhashi S, Naeini Y, Xu X, Bilchik AJ, Hoon DSB.   +8 more
europepmc   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Estimating myocardial fibrosis in aortic stenosis using the serum collagen type I C-terminal telopeptide to matrix metalloproteinase-1 ratio. [PDF]

MedComm (2020)
Gersch S, Bengel P, Paul NB, Ravassa S, von Haehling S, Fischer A, Zeisberg EM, Puls M, Hasenfuß G, Schnelle M.   +9 more
europepmc   +1 more source

Inhibition Effect of Physalis angulata Leaf Extract on Viability, Collagen Type I, and Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) but Not Plasminogen Activator Inhibitor-1 (PAI-1) of Keloid Fibroblast Culture. [PDF]

Clin Cosmet Investig Dermatol, 2023
Widiatmoko A, Fitri LE, Endharti AT, Murlistyarini S, Brahmanti H, Yuniaswan AP, Ekasari DP, Rasyidi F, Nahlia NL, Safitri PR.   +9 more
europepmc   +1 more source

Airborne 1O2 Delivery via a Superhydrophobic Dressing as a Pathway to Next‐Generation Wound Therapies, an in Vivo Murine Burn Model Study

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the SH bandage placed on an infected burn wound and its role in wound healing. A superhydrophobic PDMS membrane coated with the PS verteporfin is placed over the wound area and illuminated with a red laser at 690 nm, generating airborne 1O2 above the tissue.
Fernanda Viana Cabral, QianFeng Xu, Natalie Eidenschink, Pareesha Haresh, Alessandra Nara de Souza Rastelli, Jeremy Goverman, Alexander Greer, Alan M. Lyons, Tayyaba Hasan   +8 more
wiley   +1 more source

Human collagen type I‑based scaffold retains human‑derived fibroblasts in a patient‑derived tumor xenograft mouse model. [PDF]

Exp Ther Med
Okami H, Muranushi R, Yokobori T, Erkhem-Ochir B, Dorjkhorloo G, Seki T, Okuyama T, Fukushima R, Kawai S, Hoshino K, Dolgormaa G, Hagiwara K, Yamanaka T, Ishii N, Tsukagoshi M, Igarashi T, Watanabe A, Kubo N, Araki K, Saeki H, Shirabe K.   +20 more
europepmc   +1 more source

rSjP40 Inhibited the Activity of Collagen Type I Promoter via Ets-1 in HSCs. [PDF]

Front Cell Dev Biol, 2021
Li J, Zhang J, Zhang B, Chen L, Chen G, Zhu D, Chen J, Duan L, Duan Y.   +8 more
europepmc   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

[Retracted] MicroRNA‑642a‑5p inhibits colon cancer cell migration and invasion by targeting collagen type I α1. [PDF]

Oncol Rep
Wang X, Song Z, Hu B, Chen Z, Chen F, Cao C.   +5 more
europepmc   +1 more source