Results 261 to 270 of about 646,289 (307)

Dermal collagen fibrils are hybrids of type I and type III collagen molecules

Journal of Structural Biology, 1990
It has been suggested that dermal collagen fibrils with 67-nm periodicity consist of hybrids of type I and type III collagens. This is based on the assumption that all these banded fibrils are coated with type III collagen regardless of their diameter. However, conclusive evidence for this form of hybridization is lacking.
R, Fleischmajer, E D, MacDonald, J S, Perlish, R E, Burgeson, L W, Fisher   +4 more
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Type I Collagen and Collagen Mimetics as Angiogenesis Promoting Superpolymers

Current Pharmaceutical Design, 2007
Angiogenesis, the development of blood vessels from the pre-existing vasculature, is a key component of embryogenesis and tissue regeneration. Angiogenesis also drives pathologies such as tumor growth and metastasis, and hemangioma development in newborns.
T, Twardowski, A, Fertala, J P R O, Orgel, J D, San Antonio   +3 more
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Type I and Type III Collagens in Cutaneous Mucinosis

The American Journal of Dermatopathology, 1998
Cutaneous mucinoses are a heterogeneous group of diseases characterized by the focal or diffuse dermal deposition of glycosaminoglycans. The histopathologic examination of many cutaneous mucinoses reveals that the collagen fibers are fragmented. We wanted to characterize the type I (COL1) and type III (COL3) collagen distribution in skin biopsy ...
M F, Alves, A L, Filgueira, D E, Lorena, L C, Porto   +3 more
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Structure of equine type I and type II collagens

American Journal of Veterinary Research, 1994
Summary Collagen type I was purified from equine skin and flexor tendon, and type II collagen was purified from equine articular cartilage. The proteoglycans in these tissues were extracted, using guanidine hcl; the collagens were solubilized, using pepsin digestion, then were selectively precipitated with NaCl.
R J, Todhunter, J A, Wootton, G, Lust, R R, Minor   +3 more
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Collagen Type I: A Versatile Biomaterial

2018
Collagen type I is the most abundant matrix protein in the human body and is highly demanded in tissue engineering, regenerative medicine, and pharmaceutical applications. To meet the uprising demand in biomedical applications, collagen type I has been isolated from mammalians (bovine, porcine, goat and rat) and non-mammalians (fish, amphibian, and sea
Shiplu Roy, Chowdhury, Mohd Fauzi, Mh Busra, Yogeswaran, Lokanathan, Min Hwei, Ng, Jia Xian, Law, Ude Chinedu, Cletus, Ruszymah, Binti Haji Idrus   +6 more
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Immunohistochemical study of type I collagen and type I pN-collagen in benign and malignant ovarian neoplasms

Cancer, 1995
Type I collagen is a major constituent of the interstitial connective tissue. Although ovarian carcinoma is known to induce the expression of type I collagen in the peritoneal cavity, the distribution and metabolic activity of this collagen in ovarian tumor tissue are not known.The distributions and staining intensities of different molecular forms of ...
G G, Zhu, L, Risteli, M, Mäkinen, J, Risteli, A, Kauppila, F, Stenbäck   +5 more
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Targeting type I collagen for cancer treatment

International Journal of Cancer, 2022
AbstractCollagen is the most abundant protein in animals. Interactions between tumor cells and collagen influence every step of tumor development. Type I collagen is the main fibrillar collagen in the extracellular matrix and is frequently upregulated during tumorigenesis.
Run Shi, Zhe Zhang, Ankai Zhu, Xingxing Xiong, Jie Zhang, Jiang Xu, Man‐Sun Sy, Chaoyang Li   +7 more
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Intermolecular interactions in type I collagens

Journal of Molecular Recognition, 1992
AbstractX‐PLOR modelling of collagen dimers containing Gly‐Glu‐Arg in each chain has been carried out. The interaction between molecules when two Gly_Glu‐Arg are present on each chain is found to be substantially less than two times that obtained with one per chain, implying that relative tilting of two collagen molecules does not offset the ...
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Dual Effects of Type II Collagen on the Degradation of Type I Collagen by Tadpole Collagenase

Collagen and Related Research, 1981
Kinetic analysis of the degradation of mixtures of type I and type II collagens by tadpole collagenase was performed, using [14C]glycine-labeled type I collagen and [3H]acetylated type II collagen as substrates. The degradation rate of type I collagen was decreased in the initial stage of the reaction, then further slowed down giving a constant rate ...
H, Sunada, T, Hayashi, H, Hori, Y, Nagai
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Comparison of Axial Banding Patterns in Fibrils of Type V Collagen and Type I Collagen

Collagen and Related Research, 1987
Type V collagen and type I collagen were obtained from human placenta, essentially by salt fractionation. Precipitates were formed from mixed solutions of type V collagen and type I collagen in various ratios. They were incubated at 37 degrees C for 1 hour and negatively stained with 0.5% uranyl acetate (pH 4.4) at 37 degrees C.
E, Adachi, T, Hayashi
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