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Asian Journal of Andrology, 2022 This study explored the usefulness of two-dimensional shear wave elastography (2D-SWE) in the early assessment of corpora cavernosa fibrosis (CCF). New Zealand male rabbits were randomly assigned to an experimental group or a control group.
Li Yu +3 more
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Tendinopathy—from basic science to treatment [PDF]
, 2008 Chronic tendon pathology (tendinopathy), although common, is difficult to treat. Tendons possess a highly organized fibrillar matrix, consisting of type I collagen and various 'minor' collagens, proteoglycans and glycoproteins.
A McCormick +69 more
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Multiple antigenic determinants on type III collagen [PDF]
Biochemical Journal, 1991 Eight monoclonal antibodies have been produced against human pepsin-soluble type III collagen. All antibodies were shown to be highly specific for type III collagen and did not cross-react with a range of other collagen types or connective-tissue proteins. Examination of type III collagen from other species showed that these antibodies had a wide range
J A, Werkmeister, J A, Ramshaw
openaire +2 more sources
Molecules, 2021 Left untreated, nonalcoholic fatty liver disease can progress to nonalcoholic steatohepatitis (NASH), fibrosis, and end-stage liver disease. To date, few if any therapies have proven effective against NASH with fibrosis.
Anthony J. Pellicano +4 more
doaj +1 more source
Multifactor complex containing B element binding factor, BBF, and repressors regulate the human alpha 1(III) collagen gene (COL3A1). [PDF]
, 2006 Type III collagen is found in fetal skin and blood vessels. Previously, we characterized the proximal promoter of the human alpha1(III) collagen gene (COL3A1) using the human rhabdomyosarcoma cell line, A204, and NIH3T3 cells (Yoshino et al., Biochim ...
Matsuo, Noritaka +4 more
core +1 more source
Radiation increases COL1A1, COL3A1, and COL1A2 expression in breast cancer
Open Medicine, 2022 Radiotherapy-associated secondary cancer is an important issue for the treatment of breast cancer (BCa). This study aimed to investigate the molecular mechanism and genetic risk factors for radiation-associated secondary diseases in BCa.
Yao Guorong +3 more
doaj +1 more source
The novel missense mutation Met48Lys in FKBP22 changes its structure and functions. [PDF]
, 2020 Mutations in the FKBP14 gene encoding FKBP22 (FK506 Binding Protein 22 kDa) cause kyphoscoliotic Ehlers-Danlos Syndrome (kEDS). The first clinical report showed that a lack of FKBP22 protein due to mutations causing nonsense-mediated decay of the mRNA ...
Bächinger, Hans Peter +7 more
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Genotype-phenotype correlation study in 364 osteogenesis imperfecta Italian patients [PDF]
, 2019 Osteogenesis imperfecta (OI) is a rare genetic disorder of the connective tissue and 90% of cases are due to dominant mutations in COL1A1 and COL1A2 genes.
Boarini, Manila +11 more
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Increased expression of collagens, transforming growth factor-β1, and -β3 in gluteal muscle contracture [PDF]
, 2010 Backgroud Gluteal muscle contracture (GMC) is a multi-factor human chronic fibrotic disease of the gluteal muscle. Fibrotic tissue is characterized by excessive accumulation of collagen in the muscle's extracellular matrix.
Chen-Guang Zhao +4 more
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Toward the biochemical assessment of myocardial fibrosis in hypertensive patients [PDF]
, 1995 The serum concentrations of amino-terminal procollagen type III and carboxy-terminal procollagen type I-derived peptides, which have been proposed as useful markers of the tissue synthesis of collagen types III and type I, respectively, were abnormally ...
Diez-Martinez, J. (Javier) +5 more
core +1 more source