Results 31 to 40 of about 325,654 (266)

Model testing and mechanical analysis of frictional resistance in rock pipe jacking through water-rich fractured strata

open access: yesJournal of Highway and Transportation Research and Development
Rock pipe jacking in water-rich fractured strata presents considerable construction challenges due to significant disturbance of the surrounding rock.
Chao Zhang   +5 more
doaj   +1 more source

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

La argumentación jurídica en la toma de decisión judicial

open access: yesRevista Vasca de Administración Pública, 2014
The judicial decision making is not only a mental activity but it has an argumentative part that if it is taken into account can improve the decision. A theory about the legal reasoning that deals with the context of discovery allows to establish in a ...
Francisco Javier Ezquiaga Ganuzas
doaj   +1 more source

Self-gravitational system. New approach

open access: yesCondensed Matter Physics, 2006
The field theory approach to statistical description of the system of gravitational interacting particles is proposed in order to describe spatially inhomogeneous structures.
B.I.Lev, K.V.Grigorishin
doaj   +1 more source

In the Climate Emergency, Conservation Must Become Survival Ecology

open access: yesFrontiers in Conservation Science, 2021
Earth faces a climate emergency which renders conservation goals largely obsolete. Current conservation actions are inadequate because they (i) underplay biodiversity's role in maintaining human civilisation, which contributes to its marginalisation, and
Charlie J. Gardner, James M. Bullock
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A study of the risk ranking method of landslides and collapses

open access: yesShuiwen dizhi gongcheng dizhi, 2021
Geological disasters in China are characterized by multi-point and wide-range distribution, while the manpower and ability of geological disaster risk management and control are relatively limited.
Mingli XIE   +5 more
doaj   +1 more source

Collapsing Closures [PDF]

open access: yes, 2006
A description in the Jacobs and Langen domain is a set of sharing groups where each sharing group is a set of program variables. The presence of a sharing group in a description indicates that all the variables in the group can be bound to terms that contain a common variable. The expressiveness of the domain, alas, is compromised by its intractability.
Xuan Li, Andy King, Lunjin Lu
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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