Results 51 to 60 of about 631,811 (246)

Resolution of Exercise-Induced Syncope After Stenting of the Azygos Vein in a Dog with Segmental Aplasia and Azygos Continuation of the Levopositioned Caudal Vena Cava

open access: yesAnimals
A 1-year-old Maltese–Poodle mixed breed dog was referred to the cardiology service because of severe exercise intolerance and daily exercise-induced syncopal episodes. Physical examination revealed no abnormalities.
Viktor Szatmári   +2 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Postintubation Hypotension and its Association with Prolonged ICU Length of Stay and ICU Mortality

open access: yesEgyptian Journal of Critical Care Medicine, 2020
Introduction Cardiovascular collapse (CVC) is a serious complication of endotracheal intubation (ETI). Many studies have evaluated incidence and risk factors for postintubation hypotension.
Amr Mohamed Elsharkawy   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Collapse and Reorganization in Social-Ecological Systems: Questions, Some Ideas, and Policy Implications

open access: yesEcology and Society, 2006
We tested the explanatory usefulness and policy relevance of Holling's (2001) "adaptive cycle" theory in exploring processes of "collapse," also called "release," and recovery in regional social-ecological systems (SESs) in Zimbabwe and Australia.
Nick Abel   +2 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Intensification of the Near Wall Collapsing Bubble Induced Jet Using an Opposite Secondary Wall

open access: yesJournal of Fluid Science and Technology, 2008
Effects of an opposite secondary wall for intensification of the liquid jet that is formed through the near wall bubble collapse were numerically investigated. The axisymmetric form of the Navier-Stokes equations was solved to predict the flow conditions
Roozbeh MOUSAVI Belfeh Teymouri   +1 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Development of a Novel Extra-Articular Device for Reducing the Weight-Bearing of the Hip Joint

open access: yesJournal of Biomechanical Science and Engineering, 2006
The morbidity associated with idiopathic osteonecrosis of the femoral head (ION) is increasing. The primary goal of treatment for ION is to prevent collapse of the femoral head. With the exception of hip arthroplasties, current joint-preserving surgeries
Go YAMAKO   +4 more
doaj   +1 more source

Progressive collapse: Past, present, future and beyond [PDF]

open access: yes
The world has seen a surge in rigorous study efforts on the progressive collapse of structures in the past few decades. These events have led to new standards and provisions in building codes of practice, many of which are still being developed and ...
Makoond, Nirvan   +5 more
core   +1 more source

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