Results 61 to 70 of about 325,654 (266)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

The Role of Foreign Harem and Queen In The Fall of The Ottoman Empire: A Siyasah Shar'iyyah Perspective

open access: yesUlumuddin
The article from this research aims to explain the role of women and foreign women in the Ottoman government, which had positive and negative impacts on the Empire. At first, the role of women was not very prominent in government.
Rahmi Rahmi   +3 more
doaj   +1 more source

Detection of Collapse and Crystallization of Saccharide, Protein, and Mannitol Formulations by Optical Fibers in Lyophilization

open access: yesFrontiers in Chemistry, 2018
The collapse temperature (Tc) and the glass transition temperature of freeze-concentrated solutions (Tg') as well as the crystallization behavior of excipients are important physicochemical characteristics which guide the cycle development in freeze ...
Jacqueline Horn, Wolfgang Friess
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

Simplified Gravity Load Collapse Dynamic Analysis of Old-Type Reinforced Concrete Frames

open access: yesConstruction Materials
The results of shaking table tests from previous studies on a one-story, two-bay reinforced concrete frame—exhibiting both shear and axial failures—were compared with nonlinear dynamic analyses using simplified models intended to evaluate the collapse ...
Konstantinos G. Megalooikonomou
doaj   +1 more source

Collapse Mechanisms of Nascent and Aged Sea Spray Aerosol Proxy Films

open access: yesAtmosphere, 2018
Sea spray aerosol (SSA) is highly enriched in marine-derived organic compounds during seasons of high biological productivity, and saturated fatty acids comprise one of the most abundant classes of molecules.
Kimberly A. Carter-Fenk   +1 more
doaj   +1 more source

The Impact of Deviation of the Stun Shot from the Ideal Point on Motor Paralysis in Cattle

open access: yesAnimals, 2020
The effect on motor paralysis of a deviation in the stun shot placement from the ideal point on cattle skulls was monitored in 627 bovine animals (271 bulls and 356 cows) stunned with a captive bolt during slaughter in a slaughterhouse.
Vladimir Vecerek   +6 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

Dynamic evolution of periodic collapse and carbon impurity distribution at the plasma boundary with magnetic islands on J-TEXT

open access: yesNuclear Fusion
Periodic collapses at the edge of Ohmic-mode plasma under Resonant Magnetic Perturbation (RMP) have been observed in the J-TEXT tokamak. These collapses occur following the field penetration.
Jiankun Hua   +9 more
doaj   +1 more source

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