Results 71 to 80 of about 513,590 (314)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

[News Clip: Bridge collapse]

, 1959
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about the collapse of a Fort Worth ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

The Role of Foreign Harem and Queen In The Fall of The Ottoman Empire: A Siyasah Shar'iyyah Perspective

Ulumuddin
The article from this research aims to explain the role of women and foreign women in the Ottoman government, which had positive and negative impacts on the Empire. At first, the role of women was not very prominent in government.
Rahmi Rahmi, Ilhamni Ilhamni, Meirison Meirison, Roza Humairoh   +3 more
doaj   +1 more source

Detection of Collapse and Crystallization of Saccharide, Protein, and Mannitol Formulations by Optical Fibers in Lyophilization

Frontiers in Chemistry, 2018
The collapse temperature (Tc) and the glass transition temperature of freeze-concentrated solutions (Tg') as well as the crystallization behavior of excipients are important physicochemical characteristics which guide the cycle development in freeze ...
Jacqueline Horn, Wolfgang Friess
doaj   +1 more source

True Collapse and False Collapse

, 1998
We emphasize that standard quantum theory (SQT) is incomplete because it doesn't describe what is experimentally observed, namely events, nor does it satisfactorily define the circumstances under which events may occur. Simple models are given (all of which have the same density matrix evolution) to illustrate schemes which claim to complete SQT. It is
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Using Support Vector Machine for Prediction Dynamic Voltage Collapse in an Actual Power System [PDF]

, 2008
—This paper presents dynamic voltage collapse prediction on an actual power system using support vector machines. Dynamic voltage collapse prediction is first determined based on the PTSI calculated from information in dynamic simulation
Mohamed , Azah, Hussain, Aini, Nizam , Muhammad   +2 more
core  

Simplified Gravity Load Collapse Dynamic Analysis of Old-Type Reinforced Concrete Frames

Construction Materials
The results of shaking table tests from previous studies on a one-story, two-bay reinforced concrete frame—exhibiting both shear and axial failures—were compared with nonlinear dynamic analyses using simplified models intended to evaluate the collapse ...
Konstantinos G. Megalooikonomou
doaj   +1 more source

Collapse Mechanisms of Nascent and Aged Sea Spray Aerosol Proxy Films

Atmosphere, 2018
Sea spray aerosol (SSA) is highly enriched in marine-derived organic compounds during seasons of high biological productivity, and saturated fatty acids comprise one of the most abundant classes of molecules.
Kimberly A. Carter-Fenk, Heather C. Allen   +1 more
doaj   +1 more source