Results 11 to 20 of about 180,602 (296)

Repositioning of clinically approved drug Bazi Bushen capsule for treatment of Aizheimer's disease using network pharmacology approach and in vitro experimental validation

open access: yesHeliyon, 2023
Aims: To explore the new indications and key mechanism of Bazi Bushen capsule (BZBS) by network pharmacology and in vitro experiment. Methods: The ingredients library of BZBS was constructed by retrieving multiple TCM databases.
Tongxing Wang   +11 more
doaj   +1 more source

Potential Utility of Natural Products against Oxidative Stress in Animal Models of Multiple Sclerosis

open access: yesAntioxidants, 2022
Multiple sclerosis (MS) is an autoimmune-mediated degenerative disease of the central nervous system (CNS) characterized by immune cell infiltration, demyelination and axonal injury.
Zheng Zha   +4 more
doaj   +1 more source

Magnetic Resonance Imaging Investigation of Neuroplasticity After Ischemic Stroke in Tetramethylpyrazine-Treated Rats

open access: yesFrontiers in Pharmacology, 2022
Ischemic stroke elicits white matter injury typically signed by axonal disintegration and demyelination; thus, the development of white matter reorganization is needed. 2,3,5,6-Tetramethylpyrazine (TMP) is widely used to treat ischemic stroke. This study
Xue-Feng Feng   +18 more
doaj   +1 more source

Effect of Neurorepair for Motor Functional Recovery Enhanced by Total Saponins From Trillium tschonoskii Maxim. Treatment in a Rat Model of Focal Ischemia

open access: yesFrontiers in Pharmacology, 2021
Trillium tschonoskii Maxim. (TTM), is a perennial herb from Liliaceae, that has been widely used as a traditional Chinese medicine treating cephalgia and traumatic hemorrhage.
Le Yang   +20 more
doaj   +1 more source

Effect and Mechanism of Catalpol on Remyelination via Regulation of the NOTCH1 Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Promoting the differentiation of oligodendrocyte precursor cells (OPCs) is important for fostering remyelination in multiple sclerosis. Catalpol has the potential to promote remyelination and exert neuroprotective effects, but its specific mechanism is ...
Yaqin Sun   +6 more
doaj   +1 more source

Mobile Collateral versus Immobile Collateral [PDF]

open access: yesJournal of Money, Credit and Banking, 2022
AbstractThe financial architecture prior to the recent financial crisis was a system of mobile collateral. Safe debt, whether government bonds or privately produced bonds, that is, asset‐backed securities, could be traded, posted as collateral, and rehypothecated, moving to their highest value use.
GARY GORTON, TOOMAS LAARITS, TYLER MUIR
openaire   +2 more sources

Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes

open access: yesFrontiers in Cellular Neuroscience, 2023
2,3,5,6-Tetramethylpyrazine (TMP) as an active ingredient extracted from a traditional Chinese herbal medicine Ligusticum chuanxiong Hort. has been proved to penetrate blood-brain barrier (BBB) and show neuroprotective effects on cerebral ischemia ...
Xue-feng Feng   +16 more
doaj   +1 more source

Collateralized Networks [PDF]

open access: yesSSRN Electronic Journal, 2019
This paper studies the spread of losses and defaults in financial networks with two interrelated features: collateral requirements and alternative contract termination rules. When collateral is committed to a firm’s counterparties, a solvent firm may default if it lacks sufficient liquid assets to meet its payment obligations.
Samim Ghamami   +2 more
openaire   +2 more sources

The Republic of Serbia repo market [PDF]

open access: yesBankarstvo, 2021
The purpose of this paper is to analyze the following aspects of the Republic of Serbia repo market: legislative frame in order to identify all documents related to repo market, the main repo market features and its role, institutional frame and ...
Jeremić Ivana
doaj   +1 more source

Digital Collateral

open access: yesThe Quarterly Journal of Economics, 2021
Abstract A new form of secured lending using “digital collateral” has recently emerged, most prominently in low- and middle-income countries. Digital collateral relies on lockout technology, which allows the lender to temporarily disable the flow value of the collateral to the borrower without physically repossessing it.
Gertler, Paul   +2 more
openaire   +4 more sources

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