Results 101 to 110 of about 903,632 (373)

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease [PDF]

, 2013
Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF).
Antonio Amodeo, BIONDI ZOCCAI, GIUSEPPE, CALOGERO, ANTONELLA, CAVARRETTA, Elena, CHIMENTI, ISOTTA, DE FALCO, ELENA, Fabrizio D'Ascenzo, FRATI, GIACOMO, Luca Pacini, MANCONE, Massimo, Maria Emiliana Caristo, MARULLO, Antonino, Marzia Lotrionte, Omar Leoni, PERUZZI, MARIANGELA, PETROZZA, Vincenzo   +15 more
core   +3 more sources

Immediate remote ischemic postconditioning reduces cerebral damage in ischemic stroke mice by enhancing leptomeningeal collateral circulation

Journal of Cellular Physiology, 2018
Remote ischemic postconditioning (RIPC) is a promising neuroprotective strategy for ischemic stroke. Here, we employed a focal ischemic stroke mouse model to test the hypothesis that poststroke collateral circulation as a potent mechanism of action ...
Ying Zhang, Longhui Ma, Changhong Ren, Kaiyin Liu, X. Tian, Di Wu, Yuchuan Ding, Junfa Li, C. Borlongan, X. Ji   +9 more
semanticscholar   +1 more source

Relationship between stroke etiology and collateral status in anterior circulation large vessel occlusion

Journal of Neurology, 2020
Clinical outcome after mechanical thrombectomy (MT) for large vessel occlusion (LVO) stroke is influenced by the intracerebral collateral status. We tested the hypothesis that patients with preexisting ipsilateral extracranial carotid artery stenosis ...
Eva Hassler, M. Kneihsl, H. Deutschmann, N. Hinteregger, M. Magyar, Ulrike Wiesspeiner, Melanie Haidegger, S. Fandler-Höfler, Sebastian Eppinger, K. Niederkorn, C. Enzinger, F. Fazekas, T. Gattringer   +12 more
semanticscholar   +1 more source

Photothermal–Immunomodulatory Hydrogel Reinforced by Ti3C2/ZnAl‐LDH Nanoplatform for Eradicating MRSA and Promoting Diabetic Wound Healing

Advanced Science, EarlyView.
A NETs‐inspired Ti3C2/LDH hydrogel integrates trapping, ROS boosting, and M2‐immunomodulation for MRSA‐infected wound repair. ABSTRACT MRSA infections give rise to chronic cutaneous and advance into profound tissue invasions, including osteomyelitis and sepsis—conditions for which existing clinical interventions offer only limited efficacy. The utility
Qiang Shi, Renliang Zhao, Jia Wang, Zhenchen Xiong, Xiangtian Deng, Cheng Zheng, Wenzhi Zhang   +6 more
wiley   +1 more source

Decoding Coronary Collateral Circulation: Predictive Value of the Systemic Immune-Inflammation Index

Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College
Objective: The current study was designed to determine the association between the Systemic Immune-Inflammation Index (SII) and the degree of coronary collateral circulation in patients with stable coronary artery disease.
SHAZIA NAZAR, Muhammad Tanveer Alam, Mozaffer Rahim Hingorjo, Sumaira Riffat, Muhammad Khalid Siddiqui, Zainab Askari   +5 more
doaj   +1 more source

Glycemic disorders and coronary collateral circulation

Сахарный диабет, 2013
Although collateral circulation is the essential means of perfusion for ischemized myocardium, its efficiency varies substantially within and between the species. There is both experimental and clinical evidence for association of glycemic disorders with
Ivan Vasil'evich Starostin, K A Talitskiy, O S Bulkina, Yury Alexandrovich Karpov   +3 more
doaj   +1 more source

Relevance of the cerebral collateral circulation in ischaemic stroke: time is brain, but collaterals set the pace.

Swiss medical weekly, 2017
Blood supply to the brain is secured by an extensive collateral circulation system, which can be divided into primary routes, i.e., the Circle of Willis, and secondary routes, e.g., collaterals from the external to the internal carotid artery and ...
Simon Jung, R. Wiest, J. Gralla, Richard McKinley, H. Mattle, D. Liebeskind   +5 more
semanticscholar   +1 more source

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

Advanced Science, EarlyView.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro‐Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci   +6 more
wiley   +1 more source

An indicator of sudden cardiac death during brief coronary occlusion: electrocardiogram QT time and the role of collaterals [PDF]

, 2017
Aims The coronary collateral circulation has a beneficial role regarding all-cause and cardiac mortality. Hitherto, the underlying mechanism has not been clarified.
de Marchi, Stefano F., Delacrétaz, Etienne, Gloekler, Steffen, Meier, Pascal, Seiler, Christian, Zbinden, Rainer   +5 more
core