Results 51 to 60 of about 658,159 (250)

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources

Comparison between modified Allen’s test and Barbeau test for the assessment of hands’ collateral circulation before arterial puncture among critically ill patients

International Journal of Africa Nursing Sciences, 2021
Background: Continuous monitoring of critically ill patients requires an important procedure as arterial puncture. The first site of choice for arterial puncture is radial artery.
Ahmed Mohamed Zarea, Nadia Taha Ahmed, Suad Elsayed Abdelmotalb Elsaman   +2 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Association of Plasma Metabolic Biomarker Sphingosine-1-Phosphate With Cerebral Collateral Circulation in Acute Ischemic Stroke

Frontiers in Physiology, 2021
Background: The contribution of metabolic profile to the cerebral collateral circulation in acute ischemic stroke (AIS) has not been fully outlined.
Fang Yu, Xianjing Feng, Xi Li, Zeyu Liu, Di Liao, Yunfang Luo, Minping Wei, Qin Huang, Lin Zhang, Jian Xia, Jian Xia, Jian Xia   +11 more
doaj   +1 more source

The pathophysiology of the collateral circulation (arteriogenesis) [PDF]

The Journal of Pathology, 2000
Since the mid 1980s a new strategy is coming from bench to bedside termed angiogenesis. This process involves sprouting of capillaries and finally results in newly developed microvessels which belong to the capillary level. Importantly these newly formed capillary tubes lack vascular smooth muscle cells, they are not surrounded by mural cells and are ...
I, Buschmann, W, Schaper
openaire   +2 more sources

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Collateral Circulation and Rabep2 Polymorphisms in Large Artery Occlusion: Impacts on Short‐ and Long‐Term Prognosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Intracranial anterior circulation large artery occlusion (AC‐LAO) is a predominant cause of ischemic stroke. Although collateral circulation plays a critical role in stroke outcomes, the genetic and environmental factors affecting collateral ...
Kun Zhang, Luji Liu, Tong Li, Rui Wang, Kailin Bu, Pandi Zhao, Xiaoyun Liu   +6 more
doaj   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

The association between single-point insulin sensitivity estimator and high-sensitivity C-reactive protein with collateral circulation in coronary chronic total occlusion

Frontiers in Endocrinology
BackgroundThe single-point insulin sensitivity estimator (SPISE) is a novel metric used to assess insulin resistance. However, its association with collateral circulation impairment in patients with chronic total occlusion (CTO) remains unclear.
Yazhao Sun, Xiao Yu, Chunlan Bai, Jie Huang   +3 more
doaj   +1 more source

The coronary collateral circulation revisited [PDF]

Netherlands Heart Journal, 2013
The coronary collateral circulation constitutes a vascular network that forms bridges between adjacent arteries. In response to obstructive coronary artery disease (CAD) due to atherosclerotic plaque progression, these bridging vessels enlarge by a complex interplay of physical forces along with molecular and cellular players.
Hakimzadeh, N., Piek, J. J.
openaire   +3 more sources