Results 151 to 160 of about 7,287,837 (290)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

George Gissing, Collected Works of George Gissing on Charles Dickens, Volume 2 : Charles Dickens : A Critical Study

Cahiers Victoriens et Edouardiens, 2005
Christine Huguet (Lille III)
doaj   +1 more source

Functional Nanocomposites: Preparation, Characterization and Applications. [PDF]

Materials (Basel)
Wasilewska M, Sternik D.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Machine learning for enhancing the ablation outcomes using recurrence quantification analysis in human persistent atrial fibrillation. [PDF]

Front Physiol
Qaqos NN, Schlindwein FS, Ng GA, Li X.
europepmc   +1 more source

[Baldwin Locomotive Works, Class 8-30-D, 738, Stock]

Verso: Negative No. 9660, The Baldwin Locomotive Works, Class 8-30-D, 738, Built for Stock.
Baldwin Locomotive Works
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

From the Past to the Present and towards Possible Futures: The Collected Works of Norbert Elias (Zpráva o konferenci)

Historická sociologie, 2014
Jiří Šubrt
doaj   +1 more source

Haemophilus ducreyi Bacteria Causing Cutaneous Ulcer Outbreak in Children, Sierra Leone, December 2025. [PDF]

Emerg Infect Dis
Zhang J, Lv P, Zhao T, Jiang H, Squire JS, Yonnie MS, Koroma Z, Kamara IF, Jalloh AA, Pei G, Wang Y, Liu H, Jalloh MB, Mi Z.   +13 more
europepmc   +1 more source