Results 161 to 170 of about 3,127,959 (296)
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Protocol for evaluation of Movember's scaling what works grant funding program: Supporting the delivery of mental health interventions for men & boys in Australia, Canada and the United Kingdom. [PDF]
Steele T +12 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Dataset on the physicochemical properties of raw and torrefied tropical hardwood sawdust under varying torrefaction conditions. [PDF]
Samad NAFA, Saleh SB.
europepmc +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Historical Blood Serum Samples from Wilmington, North Carolina: The Importance of Ultrashort-Chain Per- and Polyfluoroalkyl Substances. [PDF]
Cheng L +6 more
europepmc +1 more source
01. FIRST REPORT OF THE MINE RESCUE APPARATUS RESEARCH COMMITTEE || 02. SECOND REPORT OF THE MINE RESCUE APPARATUS RESEARCH COMMITTEE. || 03. PHYSICAL EXERTION, FITNESS AND BREATHING. || 04. PHYSICAL WORK AND THE HUMAN MACHINE. || 05. THE MILITARY PHYSICAL TEST STATION, EDINBURGH. || 06. PREPARATION and PROPERTIES of HIGHLY ACTIVATED
openaire +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

