Results 111 to 120 of about 2,862,152 (305)

Designing Collectives, Designing Collectivity

open access: yes, 2023
Architecture’s Afterlife interviews have defied any rigid categorization, supporting the argument that the mentioned 38% is not “other than architecture,” or at least not completely. This percentage is understood as practitioners whose work is complementary, even instrumental to architecture.
openaire   +1 more source

Automatic water inventory, collecting, and dispensing unit [PDF]

open access: yes, 1972
Two cylindrical tanks with piston bladders and associated components for automatic filling and emptying use liquid inventory readout devices in control of water flow.
Hall, J. B., Jr., Williams, E. F.
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Kolekcjoner na rozdrożach. Jan Działyński i kórnicka kolekcja dzieł sztuki w drugiej połowie XIX wieku – ekspozycja pomiędzy romantycznym duchem patriotyzmu a nowoczesnym ujęciem naukowym

open access: yesRIHA Journal, 2011
W drugiej połowie XIX wieku w europejskim kolekcjonerstwie wyróżniała się tendencja naukowego podejścia do zbieractwa. Kolekcjonerzy nawiązywali kontakty ze znawcami i badaczami sztuki, aby tworzyć zbiory najwyższej klasy.
Kłudkiewicz, Kamila
doaj  

Exploring Consumer Collecting Behavior: A Conceptual Model and Research Agenda [PDF]

open access: yes, 2018
Purpose The purpose of this paper is to explore the behaviors that revolve around collecting, the motivations behind these behaviors and the psychological benefits collectors receive from engaging in these collecting behaviors.
Spaid, Brian I.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Glancing incidence telescopes for space astronomy [PDF]

open access: yes
Design optimization is reported for glancing telescopes of increased collecting areas. Considered are nested geometries for X-ray and extreme ultraviolet telescopes, each of which generates only one singular principal surface.
Mangus, J. D.
core   +1 more source

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