Results 181 to 190 of about 1,532,862 (339)

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Rare Case of Collecting Duct Carcinoma With Complete Response to Nivolumab. [PDF]

Case Rep Oncol Med
Hajmusa M, Kim GE, Al Homsi MU, Abdalhadi A.   +3 more
europepmc   +1 more source

Collecting duct renin regulates potassium homeostasis in mice. [PDF]

Acta Physiol (Oxf), 2023
Xu C, Chen Y, Ramkumar N, Zou CJ, Sigmund CD, Yang T.   +5 more
europepmc   +1 more source

Angiotensin II increases fibronectin and collagen I through the β-catenin-dependent signaling in mouse collecting duct cells.

AJP - Renal Physiology, 2015
Catherina A. Cuevas, Alexis A Gonzalez, N. Inestrosa, C. Vio, Minolfa C. Prieto   +4 more
semanticscholar   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

NOS1-dependent negative feedback regulation of the epithelial sodium channel in the collecting duct.

AJP - Renal Physiology, 2015
Kelly A. Hyndman, V. Bugaj, Elena V. Mironova, J. Stockand, J. Pollock   +4 more
semanticscholar   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

Canagliflozin Inhibits Electrogenic Na+ Transport in Mouse Cortical Collecting Duct Cells. [PDF]

Function (Oxf)
Nickerson AJ, Albalawy WN, Youm EB, Joseph NA, Szekely KG, Kleyman TR, Weisz OA, Kashlan OB.   +7 more
europepmc   +1 more source

Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity.

Journal of the American Society of Nephrology, 2015
Joan Li, Usukhbayar Ariunbold, N. Suhaimi, N. Sunn, Jin-jin Guo, J. McMahon, A. McMahon, M. Little   +7 more
semanticscholar   +1 more source