Results 231 to 240 of about 1,532,862 (339)

SAGE: Spatially Aware Gene Selection and Dual‐View Embedding Fusion for Domain Identification in Spatial Transcriptomics

Advanced Science, EarlyView.
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He, Yunpei Xu, Liqing Ding, Hong‐Dong Li, Yaohang Li, Shaokai Wang   +5 more
wiley   +1 more source

Contrast-enhanced ultrasound of collecting duct carcinoma in the renal: a case report misdiagnosed as renal abscess on computed tomography scan. [PDF]

Front Oncol
Luo Y, Zhang J, Wu M, Huang Q, Liu F, Qiao L.   +5 more
europepmc   +1 more source

Overexpression of Renin in the collecting duct causes elevated blood pressure.

American Journal of Hypertension, 2013
N. Ramkumar, J. Ying, D. Stuart, D. Kohan   +3 more
semanticscholar   +1 more source

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

Triple combination of bevacizumab, gemcitabine and platinum salt in metastatic collecting duct carcinoma.

Annals of Oncology, 2013
N. Pécuchet, F. Bigot, J. Gachet, C. Massard, L. Albiges, C. Teghom, Y. Allory, A. Méjean, B. Escudier, S. Oudard   +9 more
semanticscholar   +1 more source

Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions

Advanced Science, EarlyView.
This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao, Hongli Zhang, Yating Yang, Wei‐Dong Chen, Yan‐Dong Wang   +4 more
wiley   +1 more source

Urinary sodium wasting and disrupted collecting duct function in mice with distal renal tubular acidosis mutations.

Dis Model Mech
Mungara P, MacNaughton K, Ullah AKMS, Essuman G, Chelangarimiyandoab F, Mumtaz R, Hennings JC, Hübner CA, Eladari D, Alexander RT, Cordat E.   +10 more
europepmc   +1 more source

Establishment of a nomogram to predict the overall survival of patients with collecting duct renal cell carcinoma. [PDF]

Discov Oncol
Jiang W, Zou Z, Wen L.
europepmc   +1 more source

Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane.

Proceedings of the National Academy of Sciences of the United States of America, 1995
S. Nielsen, C. Chou, D. Marples, E. Christensen, B. Kishore, M. Knepper   +5 more
semanticscholar   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source