Results 231 to 240 of about 95,573 (296)

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

The FEBS Journal, EarlyView.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese, Chiara Brignola, Stefano Marrone, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo   +5 more
wiley   +1 more source

Prognostic Value of an Early Response to Tolvaptan and Its Clinical Implications in Patients With Cirrhosis and Hepatic Edema: A Nationwide Multicenter Cohort Study

Hepatology Research, EarlyView.
In a nationwide multicenter cohort, an early response to tolvaptan (≥ 1.5‐kg weight loss within 7 days) was independently associated with improved long‐term survival in patients with cirrhosis and hepatic edema. Early initiation before renal impairment or hyponatremia may optimize treatment response and prognosis. ABSTRACT Aim Hepatic edema indicates a
Kaori Koyano, Taeang Arai, Hidenori Toyoda, Keizo Kato, Joji Tani, Suguru Ogura, Tomomi Okubo, Korenobu Hayama, Norio Itokawa, Toshifumi Tada, Akito Nozaki, Atsushi Hiraoka, Kentaro Matsuura, Toru Ishikawa, Naoto Kawabe, Tsunamasa Watanabe, Koichi Takaguchi, Asahiro Morishita, Hironao Okubo, Motoh Iwasa, Hiroki Nishikawa, Yasuhito Tanaka, Masanori Atsukawa   +22 more
wiley   +1 more source

TANC1::HTRA1 fusion in schwannomas

Brain Pathology, EarlyView.
Ilay Caliskan, Kanish Mirchia, Walter Patrick Devine, Melike Pekmezci   +3 more
wiley   +1 more source

Aquaporin‐1 differentiates intrahepatic cholangiocarcinoma from liver metastases of pancreatic ductal adenocarcinoma

Histopathology, EarlyView.
Differentiating intrahepatic CCA from PDAC metastatic to the liver is critical for the clinical management of patients with pancreatobiliary cancers. AQP1 has demonstrated an excellent discriminatory performance in this clinical scenario. Aims Differentiating intrahepatic cholangiocarcinoma (iCCA) from metastatic ductal adenocarcinoma of the pancreas ...
Leoncini Giuseppe, Barella Marco, Droz Dit Busset Michele, Gentili Marco, Bodini Beatrice, Ronchetti Simona, Cari Luigi, Mazzaferro Vincenzo   +7 more
wiley   +1 more source

Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up † [PDF]

, 2017
Algaba, F., Eisen, T., Escudier, B., Kataja, V., Khoo, V., Mulders, P., Patard, J. J., Porta, C.   +7 more
core  

Human papillomavirus‐associated adenoma of the anorectum

Histopathology, EarlyView.
Aims Human papillomavirus (HPV) is the most common sexually transmitted disease in the United States. HPV‐associated invasive anorectal adenocarcinoma has been previously described. In this study, we report the clinicopathological features of three HPV‐associated anorectal adenomas.
Paula Toro, Clifton Fulmer, Erica Savage, Xuefeng Zhang   +3 more
wiley   +1 more source

Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma [PDF]

, 2019
et al,, Hsieh, James J, Xu, Jianing
core   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

Molecular Alterations in Osteosarcomas of the Oral and Maxillofacial Region: A Scoping Review

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Given the rarity and aggressive nature of osteosarcomas (OS) in the oral and maxillofacial region, understanding their molecular alterations is essential to improve diagnosis, prognosis, and guide targeted therapies. This study aimed to map molecular alterations associated with oral and maxillofacial OS, providing an overview of the
Iara Vieira Ferreira, Reydson Alcides de Lima‐Souza, Moisés Willian Aparecido Gonçalves, Carlos Takahiro Chone, Arthur Antolini‐Tavares, Albina Altemani, Fernanda Viviane Mariano   +6 more
wiley   +1 more source

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Collecting duct carcinoma

Urologie (Heidelberg, Germany), 2022
Collecting duct carcinoma (Bellini duct carcinoma) is a very rare disease with poor prognosis. Primary tumor surgery is not advisable, even though it is the therapy of choice for suspected malignant space-occupying renal masses. Chemotherapy seems to be inferior to new therapeutic concepts based on single case reports.
Marcus, Sondermann, Marlis, Günther, Thomas, Enzmann   +2 more
openaire   +3 more sources