Results 121 to 130 of about 15,464,746 (377)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Taxonomic description of Micromonospora reichwaldensis sp. nov. and its biosynthetic and plant growth-promoting potential

open access: yesMicrobiology Spectrum
Micromonospora strains proved to be a model organism for drug discovery and plant growth promotion (PGP). Strain DSM 115977 T was subjected to polyphasic taxonomic analysis and genome mining for biosynthetic gene clusters and PGP-associated genes in ...
Imen Nouioui   +6 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets

open access: yesCommunications Biology
Predicting prokaryotic phenotypes—observable traits that govern functionality, adaptability, and interactions—holds significant potential for fields such as biotechnology, environmental sciences, and evolutionary biology.
Julia Koblitz   +3 more
doaj   +1 more source

Starter cultures of lactic acid bacteria for special diet products

open access: yesThe EuroBiotech Journal, 2017
From fresh and fermented vegetables (cucumber, sauercraut, eggplant), cereals (wheat, rice), legumes (soy) 37 cultures of lactic acid bacteria were isolated.
Bareika Hanna Aljaksandrauna   +2 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Navigating conservation strategies: linking material research on alum-treated wood from the Oseberg collection to conservation decisions

open access: yesHeritage Science, 2018
From the mid-1800s to the late 1950s, conservation by alum salts (aluminum potassium sulfate dodecahydrate)—with some variations—was a routine method for treating highly deteriorated waterlogged archaeological wood in many countries, especially in ...
Susan Braovac   +5 more
doaj   +1 more source

Duplicate Detection in the Reuters Collection [PDF]

open access: yes, 1997
While conducting some experiments with the Reuters collection, it was discovered that contained within it were a number of documents that were exact duplicates of each other (see Figure 1).
Sanderson, M.
core   +1 more source

Paging: a Collection of Short Stories [PDF]

open access: yes, 2020
Introduction: Paging is a series of thematically interconnected short stories that take place at a single fictional urban hospital center. The guiding questions that the stories explore are twofold: other than doctors and patients, what kinds of people ...
Deivasigamani, Shruthi   +1 more
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

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