Results 131 to 140 of about 13,442,224 (337)
Ethical issues surrounding e-gambling data collection [PDF]
Online gambling data collection is becoming a focus of interest for various stakeholders in the online gaming industry, since it is relevant for advertising, attracting new players, exploring new markets and trying out new products.
Griffiths, MD, Whitty, M
core
Collection of biospecimens from parent-child dyads in a community garden-based nutrition intervention: protocol and feasibility [PDF]
Amrik Singh Khalsa +7 more
openalex +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
European Organic Production Statistics:Data Collection and Dissemination [PDF]
Data collection, processing and dissemination in Europe still suffers from a lack of standardization, but the situation is getting increasingly better.
Lampkin, Nicolas +5 more
core
Known as 'Darwin's Bulldog', the biologist Thomas Henry Huxley (1825–95) was a tireless supporter of the evolutionary theories of his friend Charles Darwin. Huxley also made his own significant scientific contributions, and he was influential in the development of science education despite having had only two years of formal schooling.
openaire +4 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Rural Water Collection Patterns: Combining Smart Meter Data with User Experiences in Tanzania [PDF]
Will Ingram, Fayyaz Ali Memon
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

