The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
81 Optimizing ex vivo CAR-T cell-mediated cytotoxicity assay through multimodality imaging
Fang Tian +5 more
doaj +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Validating a remote saliva collection tool for genomic analyses in free ranging dogs. [PDF]
Cimarelli G +5 more
europepmc +1 more source
A collection of various forms of stoves, used for forcing pine plants, fruit trees, and preserving tender exotics : intended as well for the use of amateurs, as that of students in the art of gardening : the plates accompanied by ample letter-press, and a correct method shewn for drawing their elevations and sections, from the plans : with the parts at large / [PDF]
William Robertson
openalex +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Streamlining Apheresis: A Dual-Intervention Quality Improvement Initiative to Increase the Efficiency in Stem Cell Collection. [PDF]
Verriet IE +6 more
europepmc +1 more source
The Collection 6 MODIS burned area mapping algorithm and product
L. Giglio +4 more
semanticscholar +1 more source
Collecting, Collectibles, Collectors and Collections
openaire +2 more sources

