Results 171 to 180 of about 3,285,076 (268)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Strategies for collection, management, and release of data for multi-site longitudinal studies: Lessons from the ABCD Data Analysis, Informatics, & Resource Center. [PDF]

Dev Cogn Neurosci
Linkersdörfer J, Berman S, Smith C, Ziemer L, Zhang L, Abad S, Baligh J, Berkness T, Bolden E, DeCastro A, Celhay O, Das B, Dowling G, Garcia K, Garduno L, Hagler DJ, Hoffman EA, Hong J, Kehl A, Kuperman J, LeBlanc K, Loughnan R, Nguyen M, Parekh P, Pecheva D, Shanbhag S, Thompson WK, Tsui B, Yang R, Dale AM.   +29 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The Creation of the Cardiac Society of Timor-Leste: A Major Step Forward in Timorese Cardiac Health. [PDF]

Glob Heart
Paratz ED, Nunn R, Williams J, Fitzgerald Z, Marques D, Ximenes S, Flavio R, Magno CN, da Costa Vinhas J, Viana S, Leão C, Milian W, Appelbe A, Kushwaha V, Eggleton S, Creati L, Wilson W, Bayley N, Lloyd D, Dos Santos HS.   +19 more
europepmc   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Introduction to high throughput synthesis, characterisation and optimisation of nanomaterials. [PDF]

Nanoscale Adv
Howes PD, Minelli C, Thomas MR, Hansel CS.   +3 more
europepmc   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

A labelled dataset of healthy and diseased common bean (<i>Phaseolus vulgaris</i>) from Tanzania. [PDF]

Data Brief
Mduma N, Laizer H.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Pre-arthritis stages of rheumatoid arthritis: from pathology to precision prevention. [PDF]

RMD Open
van der Helm-van Mil AHM, Raza K.
europepmc   +1 more source