Results 121 to 130 of about 5,003,360 (302)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Qualitative Case Studies in Operations Management: Trends, Research Outcomes, And Future Research Implications [PDF]
, 2011 Our study examines the state of qualitative case studies in operations management. Five main operations management journals are included for their impact on the field. They are in alphabetical order: Decision Sciences, International Journal of Operations
Barratt, Mark, Choi, Thomas, Li, Mei
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Short notice on choosing the herbarium digitization strategy
Інтродукція РослинHerbarium digitization is a strategic process that transforms physical collections into accessible, standardized, and interoperable digital format, thereby improving their preservation, accessibility, and scientific value.
Andriy Novikov
doaj +1 more source
The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions. [PDF]
Nat Commun, 2020 Littlejohns TJ +23 more
europepmc +1 more source
Environment, Health and Wealth: Towards an Analysis of Municipal Solid Waste Management in Ota, Ogun State, Nigeria [PDF]
, 2012 The management of municipal solid waste is one of the challenges facing the developing countries because governments, institutions, and private sectors have given solid waste management low priority and ignoring the implication it has on the general ...
Akinyinka , M.O., Olukanni, D. O.
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Optimization of a Capacitated Vehicle Routing Problem for Sustainable Municipal Solid Waste Collection Management Using the PSO-TS Algorithm. [PDF]
Int J Environ Res Public Health, 2020 Qiao Q, Tao F, Wu H, Yu X, Zhang M.
europepmc +1 more source