Results 71 to 80 of about 335,473 (263)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Collections as Data at Florida International University

, 2021
This presentation provides an overview of the concept of collections as data; shares information about our dLOC as Data grant initiative, a collaboration between the Digital Library of the Caribbean (dLOC), the Florida International University (FIU ...
Rogers, Jamie
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Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

DATA-KBR-BE: Facilitating data-level access to KBR’s collections for Open Science: Annual Report 2022-2023

, 2023
The DATA-KBR-BE: facilitating data-level access to KBR’s Collections for Open Science project is financed by the Belgian Science Policy Office (Belspo) as part of the Belgian Research Action through Interdisciplinary Networks, BRAIN 2.0 programme.
Chambers, Sally, Lemmers, Frédéric, Verbruggen, Christophe, Van Hulle, Dirk, De Potter, Pieterjan, Deseure, Brecht, Birkholz, Julie M., Ali, Dilawar, Milleville, Kenzo, Pham, Thuy-An, Ducatteeuw, Vincent, Lu, Tan, Van den broek, Alec, Bekius, Lamyk, Verstockt, Steven   +14 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Illinois Connecting to Collections Survey Instrument

, 2010
Electronic survey instrument disseminated through SurveyMonkey used to collect data from Illinois collecting institutions as part of the its Connecting to Collections Statewide Planning Grant.
Illinois Connecting to Collections partners
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Power to the people: end-user building of digital library collections

, 2001
Naturally, digital library systems focus principally on the reader: th e consumer of the material that constitutes the library. In contrast, this paper describes an interface that makes it easy for people to build their own library collections ...
Boddie, Stefan J., Ian H. Witten, Bainbridge, David, David Bainbridge, Witten, Ian H., Stefan J. Boddie   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Georgia's Healthy Collections Initiative Data [Part 1]

, 2009
Data exported from Survey Monkey from Georgia's Healthy Collection statewide survey. Sheet 1 of 3.Submitted by Jacob Jett (jjett2@illinois.edu) on 2012-11-06T22:39:31Z No.
Georgia Archives
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