Results 81 to 90 of about 335,473 (263)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Automatic text searching for personal photos [PDF]

, 2006
This demonstration presents the MediAssist prototype system for organisation of personal digital photo collections based on contextual information, such as time and location of image capture, and content-based analysis, such as face detection and ...
O'Connor, Noel E., Malobabić, Jovanka, O'Hare, Neil, Cooray, Saman H., Gurrin, Cathal, O\u27Hare, Neil, Smeaton, Alan F., Lee, Hyowon, O\u27Connor, Noel E., Jones, Gareth J.F., Uscilowski, Bartlomiej   +10 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Collections as Data at Indiana University and Beyond

, 2019
In response to federally-funded “Always Already Computational: Collections as Data” movement (https://collectionsasdata.github.io), the Indiana University Libraries are both exploring ways to provide access to our own digitized special collections for ...
Dalmau, Michelle
core  

Collection skeletons: declarative abstractions for data collections [PDF]

Modern programming languages provide programmers with rich abstractions for data collections as part of their standard libraries, e.g., Containers in the C++ STL, the Java Collections Framework, or the Scala Collections API.
Li, Zhibo
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

DATA-KBR-BE: Facilitating data-level access to KBR’s collections for Open Science: Annual Report 2021-2022

, 2023
The DATA-KBR-BE: facilitating data-level access to KBR’s Collections for Open Science project is financed by the Belgian Science Policy Office (Belspo) as part of the Belgian Research Action through Interdisciplinary Networks, BRAIN 2.0 programme.
Chambers, Sally, Lemmers, Frédéric, Verbruggen, Christophe, Jacquet, Antoine, Van Hulle, Dirk, Dillen, Wout, De Potter, Pieterjan, Deseure, Brecht, Birkholz, Julie M., Ali, Dilawar, Milleville, Kenzo, Pham, Thuy-An, Ducatteeuw, Vincent, Lu, Tan, Bekius, Lamyk, Verstockt, Steven   +15 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source