Results 91 to 100 of about 136,842 (256)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Humor and social norms on social media: When bible verses or memes mobilize Christians for humanitarian collective actionOpen Science Framework

Acta Psychologica
Group members' decisions on whether or not to become actively involved in collective action are often guided by social norms regarding both action and inaction.
Hedy Greijdanus, Willem van de Wetering, Casper Roos   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Cultural logics of honor, face, and dignity as moderators of the relationship between group process and pro-migrant collective action intentions

Current Research in Ecological and Social Psychology
Although group identification, efficacy, and injustice appraisals are well-established predictors of collective action support, contextual factors are rarely examined.
Tomasz Besta, Emma Thomas, Goksu Celikkol, Michał Olech, Paweł Jurek, Martijn van Zomeren, Maura Pozzi, Carlo Pistoni, Marek Palace, Gulcin Akbas, Julia C. Becker, Maja Becker, Tymofii Brik, Maria Chayinska, Makiko Deguchi, Sandesh Dhakal, Kaltrina Kelmendi, Anna Kende, Natasza Kosakowska-Berezecka, Soledad de Lemus, Paul Le Dornat, Angela K.-y. Leung, Sarah E. Martiny, Rie Mizuki, Danny Osborne, Raja Intan Arifah binti Raja Reza Shah, Pravash Kumar Raut, Saba Safdar, Katherine Stroebe, Dijana Sulejmanović, Eugene Y.J. Tee, Gonneke Ton, Özden Melis Uluğ, Ana Urbiola, Anna Wlodarczyk   +34 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Collective Action Theory: the Political Dimension

RUDN Journal of Political Science, 2011
The article is devoted to the analysis of the modern collective action theory as one of the main analytic structures dedicated to the civil society functioning.
D B Kazarinova
doaj  

Intergroup contact, outgroup knowledge and advantaged group collective action: can who you know and what you know promote social change?

Frontiers in Social Psychology
Some groups in society unjustly hold greater social, economic, and political power over others, placing some groups in more advantaged and others in more disadvantaged positions.
Caitlin Ferry, Caitlin Ferry, Cara MacInnis, Cara MacInnis, Elena Buliga   +4 more
doaj   +1 more source