Results 151 to 160 of about 5,280,218 (348)

The many meanings of collective action: lessons on enhancing gender inclusion and equity in watershed management [PDF]

open access: yes
"Collective action in agriculture and natural resource management is all too often perceived of in terms of the mere number of participants, with little consideration given to who participates, why, and the outcomes of inequitable participation.
Tanui, Joseph   +4 more
core  

Inactive and Quiescent? Immigrant Collective Action in Comparative Perspective, 1960 to 1995

open access: yesSocius
Social movement mobilization by and on behalf of immigrants occurs frequently today, but sociologists have been slow to include immigrant collective action in the canon of social movement or immigration scholarship.
Kim Voss   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Renegotiation, Collective Action Clauses and Sovereign Debt Markets [PDF]

open access: yes
Collective action clauses (CACs) are provisions specifying that a supermajority of bondholders can change the terms of a bond. We study how CACs determine governments' fiscal incentives, sovereign bond prices and default probabilities in environments ...
Federico Weinschelbaum, Jose Wynne
core  

Psychological motivations and deterrents of collective environmental action

open access: yes, 2023
openThis paper analyzes existing literature with the goal of understanding key elements that either incite or deter collective environmental action.
CORTESE, FRANCESCA ROSE
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Collective Action in Plant Breeding

open access: yes
Olson (1965) formulated a "Logic of Collective Action". We investigate whether a logic of collective action in plant breeding - and research and development generally - can be constructed. Using a case study on the Latin American Fund for Irrigated Rice (
Binenbaum, Eran, Pardey, Philip G.
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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