Results 111 to 120 of about 4,076,134 (301)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Women's Action Collective '1st Annual Famous Feminist Day' poster
, 1977 This poster advertised a fundraising benefit held by the Women's Action Collective (WAC) in Columbus, Ohio on December 3, 1977. It billed as "the 1st Annual Famous Feminist Day" and was set in honor of Alice Paul (1885-1977), an influential suffragette ...
Women's Action Collective
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Frontiers in Social PsychologySome groups in society unjustly hold greater social, economic, and political power over others, placing some groups in more advantaged and others in more disadvantaged positions.
Caitlin Ferry +4 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Collective Action-A Challenge and an Opportunity for Water Governance [PDF]
This paper addresses the motivations that drive participation in groups concerning water protection and provides a review of the key role collective action plays in accessing and managing water resources. It also analyses the conditions and factors which
Maria Manuela Castro Silva
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Psychological motivations and deterrents of collective environmental action
, 2023 openThis paper analyzes existing literature with the goal of understanding key elements that either incite or deter collective environmental action.
CORTESE, FRANCESCA ROSE
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Collective action / Action collective [PDF]
Canadian Journal of Dietetic Practice and Research, 2014 openaire +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source