Results 141 to 150 of about 4,076,134 (301)

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Collective action in poverty reduction programs

open access: yes
Over half of the hungry people in the world are small-scale farmers, herders, and fishers, who produce food but cannot reliably feed themselves and their families. Nevertheless, poor people are themselves working to improve their lives.
CGIAR Program on Collective Action and Property Rights
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Collective action for small-scale producers of agricultural biodiversity products: [PDF]

open access: yes
"The role of well-functioning markets for development is now widely recognized, however the challenge remains to make these markets benefit the poor and the environment.
Kruijssen, Froukje   +2 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Women's Action Collective 'First Annual Famous Feminist Day' fundraising event notice

open access: yes, 1977
This document notified the members and friends of the Women's Action Collective (WAC) about a fundraising event titled the "First Annual Famous Feminist Day" to support the WAC's women's center. The event celebrated Alice Paul (1885-1977), an influential
Women's Action Collective
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Critical note about the passive class action in Brazilian Law
Nota crítica ao instituto da ação coletiva passiva no direito brasileiro

open access: yesScientia Iuris, 2005
It analyzes the figure of the passive class action, concluding for the impossibility of any class action that does not have as target the guardianship of metaindividuals interests.Analisa a figura da ação coletiva passiva, concluído pelo impossibilidade ...
Clayton Maranhão
doaj  

Enabling equitable collective action and policy change for poverty reduction and improved natural resource management in the Eastern African highlands: [PDF]

open access: yes
"The role of local and external institutions in natural resource management (NRM) is gaining attention in the literature, fostering greater understanding of the relationship between collective action and poverty, collective action and equity, and the ...
Ayele, Shenkut   +17 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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