Results 41 to 50 of about 143,728 (254)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Modes of Collective Action in Village Economies: Evidence from Natural and Artefactual Field Experiments in a Developing Country [PDF]

Asian Development Review, 2013
In a canonical model of collective action, individual contribution to collective action is negatively correlated with group size. Yet, empirical evidence on the group size effect has been mixed, partly due to heterogeneities in group activities.
Yasuyuki Sawada, Ryuji Kasahara, Keitaro Aoyagi, Masahiro Shoji, Mika Ueyama   +4 more
doaj   +1 more source

Mobilising IDEAS in the COVID-19 Pandemic: Anti-Lockdown Actions and the Identity-Deprivation-Efficacy-Action-Subjective Well-Being Model

Journal of Social and Political Psychology, 2023
We tested how well the Identity-Deprivation-Efficacy-Action-Subjective-wellbeing (IDEAS) model predicts citizens’ intentions to engage in collective action opposing their government, and their subjective well-being.
Fanny Lalot, Gaëlle Marinthe, Alice Kasper, Dominic Abrams   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

COMPLEX COLLECTIVE DUTIES & ACTION-GUIDANCE

Kriterion
We can often find in the literature (both popular and academic) ascriptions of complex collective duties to extensive unstructured collections of individuals.
Cristian Rettig
doaj   +1 more source

Unplanned Coordination: Ensemble Improvisation as Collective Action

Journal of Social Ontology, 2022
The characteristic features of ensemble dance improvisation (EDI) make it an interesting case for theories of intentional collective action. These features include the high degree of freedom enjoyed by each individual, and the lack of fixed hierarchical
Ali Hasan, Jennifer Kayle
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Grass Roots Collective Action: Agricultural Opportunities

Journal of Agricultural and Resource Economics, 1997
Agroenvironmental problems (e.g., contamination of ground- and surface water, feed lot odors, endangered species) often involve goods and activities with public goods attributes.
Harry W. Ayer
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Leadership in collective action [PDF]

, 2008
We extend the model of collective action in which groups compete for a budged by endogenizing the group platform, namely the specific mixture of public/private good and the distribution of the private good to group members which can be uniform or performance-based. While the group-optimal platform contains a degree of publicness that increases in group
Joan Esteban, Esther Hauk
openaire   +2 more sources