Results 151 to 160 of about 3,971,747 (262)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Does Strengthening Collective Action Clauses (CACs) Help? [PDF]

open access: yes
We study the effect of strengthening CACs in a debt rollover model of a sovereign debt crisis. Conditional on default, there are multiple equilibria: the impact of strengthening CACs depends critically on the prevailing equilibrium.
Kannika Thampanishvong, Sayantan Ghosal
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Collective action in plant genetic resources management: gendered rules of reputation, trust and reciprocity in Kerala, India [PDF]

open access: yes
"Collective action aims at the joint management of common pool resources. Agrobiodiversity at the community level is conceptualized as a collective resource requiring the management of varieties, species and their interrelations within a farming-system ...
Padmanabhan, Martina Aruna
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Collective action and property rights for sustainable development

open access: yes
Institutions for collective action and systems of property rights shape how people use natural resources. These patterns of use in turn affect the outcomes of people's agricultural production systems.
CGIAR Program on Collective Action and Property Rights
core   +1 more source

The private solution trap in collective action problems across 34 nations. [PDF]

open access: yesProc Natl Acad Sci U S A
Malthouse E   +71 more
europepmc   +1 more source

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