Results 91 to 100 of about 1,291,148 (269)

Correction: Environmental adversity is associated with lower investment in collective actions. [PDF]

open access: yesPLoS One, 2021
Lettinga N   +4 more
europepmc   +1 more source

Emergence of universal scaling in financial markets from mean-field dynamics

open access: yes, 2010
Collective phenomena with universal properties have been observed in many complex systems with a large number of components. Here we present a microscopic model of the emergence of scaling behavior in such systems, where the interaction dynamics between ...
Sinha, Sitabhra, Vikram, S. V.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Collective Risk Management in a Flight to Quality Episode [PDF]

open access: yes
We present a model of optimal intervention in a flight to quality episode. The reason for intervention stems from a collective bias in agents' expectations. Agents in the model make risk management decisions with incomplete knowledge.
Arvind Krishnamurthy   +1 more
core  

Organizing for Justice: ILGWU Returns to Social Unionism to Organize Immigrant Workers [PDF]

open access: yes, 1993
[Excerpt] Desperate situations bring forth desperate responses. But garment workers are demonstrating that when educated of their rights and assured of support, they are ready to struggle for justice, even when chances of success seem poor.
Hermanson, Jeff
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

THE DEFENSE OF TRANSIN DIVIDUAL INTE RESTS : BRAZIL AND IBERO-AMERICA

open access: yesBRICS Law Journal, 2016
This article deals with the background, applicability and requirements of collective actions in the defense of transindividual rights and interests, both diffuse and collective, homogenous individual rights, as well as citizen’s actions in the context of
A. P. Grinover
doaj   +1 more source

Nations, Overlapping Generations and Historic Injustice [PDF]

open access: yes, 2006
This article considers the question of the responsibility that present day generations bear as a result of the actions of their ancestors. Is it morally significant that we share a national identity with those responsible for the perpetration of historic
Butt, Daniel
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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