Results 91 to 100 of about 1,068,356 (282)
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Vjesnik Istarskog Arhiva, 2021 The Irish folklore collection is a national social archive and has been an important focal point and a stabilizing influence on the development of the Irish collective identity after the foundation of the Irish Free State in 1922.
Georg Grote
doaj
, 2004 We examine in detail an alternative method of retrieving the information written into an atomic ensemble of three-level atoms using electromagnetically induced transparency.
A. V. Rybin +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
La création littéraire au carrefour de l’histoire intime et de l’histoire collective
Contextes, 2015 À travers cet article, nous nous proposons de réfléchir aux fondements sociaux de la création littéraire ainsi qu’à ses contextes de réalisation. Le choix de l’écrivain algérien francophone Rachid Boudjedra se révèle, à cet égard, particulièrement ...
Kaoutar Harchi
doaj +1 more source
Entanglement, Non-linear Dynamics, and the Heisenberg Limit
, 2009 We show that the quantum Fisher information provides a sufficient condition to recognize multi-particle entanglement in a $N$ qubit state. The same criterion gives a necessary and sufficient condition for sub shot-noise phase sensitivity in the ...
A. S. Holevo +4 more
core +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
THE MOTHER’S SPEECH PORTRAIT IN THE LINGVOCULTURE: TO THE RESEARCH PROJECT REALISATION
Вестник Кемеровского государственного университета, 2015 The paper considers the description of linguistic personality characteristics in their problematical aspect. Taking into account the means of speech portrait methodology, the paper aims at justifying the necessity of a new aspect in linguistic ...
O. N. Varlamova
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