Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
A ritual way of ageing well: a qualitative study of a comprehensive, culturally grounded ritual-based health programme for older adults in urban China. [PDF]
Zhang X, Wang Q.
europepmc +1 more source
Controlling counterion exchange rate during aqueous phase separation enables the formation of skin‐free, homogeneously porous polyelectrolyte complex hydrogels by suppressing kinetically trapped skin layers and macrovoids. The resulting hydrogel networks exhibit exceptional toughness (∼15 MJ·m−3) and enable 3D (bio)printing and post‐functionalization ...
Adrivit Mukherjee +7 more
wiley +1 more source
A comprehensive mechanistic multicellular model of the human immune system spanning 11 diseases. [PDF]
Moore R +6 more
europepmc +1 more source
Conformational Switching of Proteins on Material Surfaces Enabled by Peptide‐Oriented Adsorption
Responsive biointerfaces could be achieved using conformationally responsive proteins; however, their interconversion can be lost upon surface adsorption. Herein, we demonstrate that the incorporation a Au binding peptide into calmodulin allows for binding control on Au wherein the protein retains conformational switching. This capability was confirmed
Sakthirupini Ramamurthy +7 more
wiley +1 more source
Dengue vaccine: a hidden risk to Aedes aegypti control in Brazil. [PDF]
Golias HC.
europepmc +1 more source
An Edible Chitosan‐Based Acoustic Sensor for Sound‐Responsive Actuation in Edible Robots
This study introduces an edible acoustic sensor for robotic food and edible robotics. Built from a chitosan piezoelectric film between gold electrodes, the sensor enables acoustic communication through ON/OFF keying. Integrated into an edible robot with pneumatically actuated arms and neck, it responds to high‐frequency tones.
Valerio Francesco Annese +8 more
wiley +1 more source
Visual detection of collective highly toxic metals in water by a handheld whole-cell biosensing detector: From circuit to field. [PDF]
Pi S +7 more
europepmc +1 more source
A dynamically actuated reconfigurable topographical surface (DARTS) integrates contact‐mediated bactericidal nanotopography with programmable mechanical actuation to actively disrupt bacterial biofilms. Dynamic surface reconfiguration enhances bacterial killing and suppresses implant‐associated infections in vivo, providing a new strategy for active ...
Mohammad Asadi Tokmedash +4 more
wiley +1 more source
MIRD Pamphlet No. 34, Part 1: MIRDct-A Customizable Software Tool for CT Dosimetry. [PDF]
Ocampo Ramos JC +11 more
europepmc +1 more source

