Results 51 to 60 of about 869,083 (297)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Prospects of reinforcement learning for the simultaneous damping of many mechanical modes [PDF]

open access: yes, 2020
We apply adaptive feedback for the partial refrigeration of a mechanical resonator, i.e. with the aim to simultaneously cool the classical thermal motion of more than one vibrational degree of freedom.
Asjad, Muhammad   +2 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Community climate resilience and environmental education: Opportunities and challenges for transformative learning

open access: yesEnvironmental Education Research, 2022
Grassroots initiatives towards climate resilience in cities are likely to embed environmental education practices with potential transformative impact among young people.
I. Ruiz‐Mallén   +3 more
semanticscholar   +1 more source

The William and Flora Hewlett Foundation's Nuclear Security Initiative: Findings from a Summative Evaluation [PDF]

open access: yes, 2015
The Nuclear Security Initiative (NSI) began as an exploratory effort in 2008 and, as with other Foundation initiatives, was intended to be a time-limited effort (though the timeframe for the Foundation's exit was not specified at the outset). The NSI was

core  

Residents’ participation in energy performance certification for collective action on climate change: the case of EnerGuide

open access: yesFrontiers in Psychology, 2023
IntroductionAlthough governments have launched energy performance certification (EPC) programs to increase residential energy efficiency, residents’ perception and acceptance of these programs have been little studied. This study contextualizes residents’ intentions to participate in EPC programs in terms of their attributions to and attitudes toward ...
Xinyu Chen, Zhonghua Gou, Huihua Zhang
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Strategies and Tools to Raise Energy Awareness Collectively [PDF]

open access: yes, 2016
Providing smart meters and technology for feedback on energy consumption have been considered strategic in current energy policies as part of the battle against climate change. However, feedback alone does not always lead to energy savings.
Alani, Harith, Piccolo, Lara S. G.
core  

Ethics of Nuclear Energy in Times of Climate Change: Escaping the Collective Action Problem

open access: yesPhilosophy & Technology, 2022
AbstractIn recent years, there has been an intense public debate about whether and, if so, to what extent investments in nuclear energy should be part of strategies to mitigate climate change. Here, we address this question from an ethical perspective, evaluating different strategies of energy system development in terms of three ethical criteria ...
Simon Friederich, Maarten Boudry
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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