Results 51 to 60 of about 869,083 (297)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Prospects of reinforcement learning for the simultaneous damping of many mechanical modes [PDF]
We apply adaptive feedback for the partial refrigeration of a mechanical resonator, i.e. with the aim to simultaneously cool the classical thermal motion of more than one vibrational degree of freedom.
Asjad, Muhammad +2 more
core +3 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Grassroots initiatives towards climate resilience in cities are likely to embed environmental education practices with potential transformative impact among young people.
I. Ruiz‐Mallén +3 more
semanticscholar +1 more source
The William and Flora Hewlett Foundation's Nuclear Security Initiative: Findings from a Summative Evaluation [PDF]
The Nuclear Security Initiative (NSI) began as an exploratory effort in 2008 and, as with other Foundation initiatives, was intended to be a time-limited effort (though the timeframe for the Foundation's exit was not specified at the outset). The NSI was
core
IntroductionAlthough governments have launched energy performance certification (EPC) programs to increase residential energy efficiency, residents’ perception and acceptance of these programs have been little studied. This study contextualizes residents’ intentions to participate in EPC programs in terms of their attributions to and attitudes toward ...
Xinyu Chen, Zhonghua Gou, Huihua Zhang
openaire +3 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Strategies and Tools to Raise Energy Awareness Collectively [PDF]
Providing smart meters and technology for feedback on energy consumption have been considered strategic in current energy policies as part of the battle against climate change. However, feedback alone does not always lead to energy savings.
Alani, Harith, Piccolo, Lara S. G.
core
Ethics of Nuclear Energy in Times of Climate Change: Escaping the Collective Action Problem
AbstractIn recent years, there has been an intense public debate about whether and, if so, to what extent investments in nuclear energy should be part of strategies to mitigate climate change. Here, we address this question from an ethical perspective, evaluating different strategies of energy system development in terms of three ethical criteria ...
Simon Friederich, Maarten Boudry
openaire +3 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

