Results 41 to 50 of about 65,954 (297)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Hole-Hole Collective Excitations in 106, 112, 130Sn Isotopes

open access: yesEast European Journal of Physics, 2023
In this paper, energy-level schemes of neutron rich and reduced electric transition strengths of Tin isotopes 106Sn, 112Sn and 130Sn were studied using collective models, i.e., hole-hole Tamm-Dancoff Approximation (hh TDA) and hole-hole Random Phase ...
Fahima A. Saber, Ali H. Taqi
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Spin-flip excitations, spin waves, and magneto-excitons in graphene Landau levels at integer filling factors

open access: yes, 2010
We study collective electronic excitations in graphene in the integer quantum Hall regime, concentrating mainly on excitations with spin reversal such as spin-flip and spin-wave excitations.
Fuchs, J. -N.   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Spectrally and Spatially Resolved Smith-Purcell Radiation in Plasmonic Crystals with Short-Range Disorder

open access: yesPhysical Review X, 2017
Electrons interacting with plasmonic structures can give rise to resonant excitations in localized plasmonic cavities and to collective excitations in periodic structures.
I. Kaminer   +11 more
doaj   +1 more source

Superconducting critical temperature in the extended diffusive Sachdev-Ye-Kitaev model

open access: yesPhysical Review Research, 2021
Models for strongly interacting fermions in disordered clusters forming an array, with electron hopping between sites, reproduce the linear dependence on temperature of the resistivity, typical of the strange metal phase of high temperature ...
F. Salvati, A. Tagliacozzo
doaj   +1 more source

Collective excitations in the inner crust of neutron stars : supergiant resonances

open access: yes, 2004
We investigate the nuclear collective excitations of Wigner-Seitz cells containing nuclear clusters immersed in a gas of neutrons. This baryonic non-uniform system is specific to the structure of inner crust matter of neutron stars.
E. Khan   +5 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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