Results 101 to 110 of about 6,311,451 (328)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Probing the chiral magnetic wave with charge-dependent flow measurements in Pb-Pb collisions at the LHC

open access: yesJournal of High Energy Physics, 2023
The Chiral Magnetic Wave (CMW) phenomenon is essential to provide insights into the strong interaction in QCD, the properties of the quark-gluon plasma, and the topological characteristics of the early universe, offering a deeper understanding of ...
The ALICE collaboration   +1054 more
doaj   +1 more source

A flow paradigm in heavy-ion collisions

open access: yes, 2018
The success of hydrodynamics in high energy heavy-ion collisions leads to a flow paradigm, to understand the observed features of harmonic flow in terms of the medium collective expansion regarding initial state geometrical properties. In this review, we
Yan, Li
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Economic Factors Concerning The Migration Of The Best Educated Workers. The Case Of College Teachers

open access: yesComparative Economic Research, 2015
The migration flow of highly skilled workers is a growing and changing issue, especially under the economic conditions in recent years. This research focused on the migration of university teachers, a highly skilled collective responsible for the ...
Antonio Mihi-Ramírez   +2 more
doaj   +1 more source

Determination of the reaction plane in ultrarelativistic nuclear collisions

open access: yes, 1993
In the particles produced in a nuclear collision undergo collective flow, the reaction plane can in principle be determined through a global event analysis.
H. Bateman   +12 more
core   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Universal scaling laws of collective human flow patterns in urban regions

open access: yesScientific Reports, 2020
Detail observation of human locations became available recently by the development of information technology such as mobile phones with GPS (Global Positioning System).
Yohei Shida   +3 more
doaj   +1 more source

Superfluidity of Dirac Fermions in a Tunable Honeycomb Lattice: Cooper Pairing, Collective Modes, and Critical Currents

open access: yes, 2012
Motivated by recent experiments on atomic Dirac fermions in a tunable honeycomb optical lattice, we study the attractive Hubbard model of superfluidity in the anisotropic honeycomb lattice.
A. J. Leggett   +4 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy