Results 81 to 90 of about 4,131,535 (260)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Enhanced hydrodynamic predictions for
Physics Letters BWe present hydrodynamic predictions for the new observable v 02 ( p T ), which measures the correlation of particle spectra with elliptic flow. We implement a data-driven correction so as to match hydrodynamic calculations to elliptic flow ( v 2 ( p T ))
Rupam Samanta +2 more
doaj +1 more source
Universal scaling laws of collective human flow patterns in urban regions
Scientific Reports, 2020 Detail observation of human locations became available recently by the development of information technology such as mobile phones with GPS (Global Positioning System).
Yohei Shida +3 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Modeling collective behaviors from optic flow and retinal cues
Physical Review ResearchAnimal collective behavior is often modeled with self-propelled particles, assuming each individual has “omniscient” knowledge of its neighbors. Yet, neighbors may be hidden from view and we do not know the effect of this information loss.
Diego Castro +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Component parts of the World Heat Flow Data Collection
, 2013 This data set is a compilation of heat flow data of uncertain origin. References as cited in Global Heat Flow Database were incomplete and thus could not be verified.
Global Heat Flow Compilation Group +1 more
core +1 more source
On the mechanical interplay between intra- and inter-synchronization during collective cell migration : a numerical investigation [PDF]
, 2013 Collective cell migration is a fundamental process that takes place during several biological phenomena such as embryogenesis, immunity response, and tumorogenesis, but the mechanisms that regulate it are still unclear.
ALLENA, Rachele +3 more
core +1 more source
Can we observe effects of early nonequilibrium dynamics using collective flow [PDF]
EPJ Web of ConferencesThe rapid expansion of the fireball created in a heavy-ion collision causes strong departures from equilibrium. Such effects are especially important in the very early phase of the collision, bringing a substantial pressure asymmetry.
Bożek Piotr
doaj +1 more source