Results 71 to 80 of about 4,131,535 (260)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Youth Research Collective Life Patterns Project - Cohort 1
Life Patterns is an Australian Research Council funded project following the lives of young Australians since the 1990s. The project has followed two cohorts of young Australians during the last 30 years: Cohort 1 who were aged 18 in 1991 and Cohort 2 ...
Youth Research Collective
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Evidence for the collective nature of radial flow in Pb+Pb collisions with the ATLAS detector [PDF]
EPJ Web of ConferencesIn heavy-ion collisions, the isotropic radial expansion of the formed Quark-Gluon Plasma (QGP) has been studied using its influence on other experimental observables.
Bhatta Somadutta
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Economic Factors Concerning The Migration Of The Best Educated Workers. The Case Of College Teachers
Comparative Economic Research, 2015 The migration flow of highly skilled workers is a growing and changing issue, especially under the economic conditions in recent years. This research focused on the migration of university teachers, a highly skilled collective responsible for the ...
Antonio Mihi-Ramírez +2 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Congestion Number Analysis of Cross-Flow Dynamics: Experimental Data and Simulations [PDF]
We recently proposed the "Congestion Number" (CN) as a metricto evaluate the state of a pedestrian crowd. Such metric, whose definition is based on the gradient of the rotor of the crowd velocity field, appears to provide additional information with ...
Yucel, Zeynep +4 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Bridging the gap Why we need to enhance current simulation models [PDF]
, 2020 Many models that simulate evacuations are state of the art and provide realistic insight to their users. However, simulating everyday situations, such as visitor flow through a museum or passenger flow through an airport, presents marked challenges ...
Angelika, Kneidl
core +1 more source