Results 121 to 130 of about 2,629,932 (295)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Nostalgia as enabler of self-continuity

, 2008
In 1969, Crosby, Stills, Nash, and Young released their self-titled album containing the classic song "Suite: Judy Blue Eyes." A particularly striking lyric from this song recommended: "Don't let the past remind us of what we are not now." This evocative
Sedikides, Constantine, Arndt, Jamie, Gaertner, Lowell, Routledge, Clay, Wildschut, Tim   +4 more
core   +1 more source

From collective efficacy and negative emotions toward management and conservation of wetlands: the mediating role of social identity

Frontiers in Psychology
Wetlands are among the most valuable natural resources on Earth. However, many have been destroyed in recent decades. One suggested solution for their sustainable use is the creation of collective management and protection strategies.
Naser Valizadeh, Vahid Karimi, Khadijeh Bazrafkan, Hossein Azadi, Hassan Azarm   +4 more
doaj   +1 more source

Testing the effect of historical representations on collective identity and action. [PDF]

PLoS One, 2020
Makanju D, Livingstone AG, Sweetman J.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Trajectories of identity change : explaining the persistence of collective opposition [PDF]

, 2009
This article explores the micro-level mechanisms that reproduce collective opposition. It uses a typology of identity change to compare individual narratives in two situations where there are strong incentives to change and different outcomes: religious ...
Todd, Jennifer
core   +1 more source

Names and Collective Identity

Oslo Studies in Language, 2012
The preceding two decades have displayed a remarkable awareness for a connection between the concepts "identity" and "cultural memory". David Lowenthal speaks of a "current craze for heritage"! Cultural heritage has become extremely popular, especially in combination with tourism, and has accordingly been converted into a modern system of meaning a ...
openaire   +2 more sources

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source