Results 61 to 70 of about 2,912,779 (278)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Consistent Individual Differences Drive Collective Movements in a Tibetan Macaque Group

Animals
Collective movement has emerged as a key area of interest in animal behavior. While individual differences are often viewed as a potential threat to group cohesion, growing evidence suggests that these differences can actually influence an animal’s ...
Sen Ren, Shenqi Liu, Wenkai Sun, Lei Gao, Lei Ren, Jiahui Liu, Weiqi Zhang, Dongpo Xia, Binghua Sun, Jinhua Li, Xi Wang   +10 more
doaj   +1 more source

The Dalit Women's Movement in India

, 2009
The Anandi Collective describes the way feminists and Dalit leaders worked to build a movement of Dalit women. They describe the challenges and successes of the 1,600 Dalit women from a remote area in a very feudal part of India, who have set out to ...
Anandi Collective
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Self-organized aggregation–dispersion dynamics in schooling fish [PDF]

Royal Society Open Science
The collective behaviour of fish can promote the propagation of social information within the group, benefiting the individuals within the group.
Zhen Kang, Zhangang Han
doaj   +1 more source

Social flocculation in plant–animal worms [PDF]

Royal Society Open Science, 2019
Individual animals can often move more safely or more efficiently as members of a group. This can be as simple as safety in numbers or as sophisticated as aerodynamic or hydrodynamic cooperation.
Alan Worley, Ana B. Sendova-Franks, Nigel R. Franks   +2 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

BETWEEN THE RESTRUCTURING AND THE EXPANSION OF THE BRAZILIAN FEDERAL UNIVERSITIES: MOVEMENTS THAT SINGLE OUT THE CROSSING OF THE FEDERAL UNIVERSITY OF PELOTAS / ENTRE A REESTRUTURAÇÃO E A EXPANSÃO DAS UNIVERSIDADES FEDERAIS BRASILEIRAS: MOVIMENTOS QUE SINGULARIZAM A TRAVESSIA DA UNIVERSIDADE FEDERAL DE PELOTAS

Didasc@lia: didáctica y educación, 2011
In the present article, it is analyzed the academic implications between space and curricular design – guide-lines from the program REUNI/MEC –in the context of the Federal University of Pelotas.
Eliana Povoas Brito, Roberto Heiden
doaj  

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source