Results 71 to 80 of about 2,912,779 (278)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Collective Nostalgia Is Associated With Stronger Outgroup-Directed Anger and Participation in Ingroup-Favoring Collective Action

Journal of Social and Political Psychology, 2017
Collective nostalgia refers to longing for the way society used to be. We tested whether collective nostalgia is associated with ingroup-favoring collective action and whether this association is mediated by outgroup-directed anger and outgroup-directed ...
Wing-Yee Cheung, Constantine Sedikides, Tim Wildschut, Nicole Tausch, Arin H. Ayanian   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

“Doing It for Yourself”: Collective Action at a Personalist Blended Social Movement Organization

Socius
Social movement scholars assert that collective action depends on the construction of a robust collective identity within social movements. Yet the author witnessed a particularly weak collective identity over two years of observation and interviews at ...
Adam Kotanko
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Collecting Mandible Movement in Brazilian Portuguese

Interspeech 2024
This paper reports on a corpus of Brazilian Portuguese (BP) mandible movements. The data was collected using a recently available technique, the MARRYS helmet, which allows for quick and reliable collection of mandible data of a large number of speakers. Audio and mandible were recorded from more than 90 L1 and L2 BP speakers. The recording process and
Donna Erickson, Albert Rilliard, Malin Svensson Lundmark, Adelaide Silva, Leticia Rebollo Couto, Oliver Niebuhr, João Antônio de Moraes   +6 more
openaire   +1 more source

Collective identity and action of the Gulen movement : implications for social movement theory

, 2008
This study focuses on the collective identity, action and outcomes of the Gülen Movement within the framework of sociology of social movements. It differs from recent studies in that, rather than using the categorizations from one theory, it tests ...
Cetin, Muhammed
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Collective Movement of Sediment in Littoral Environment

Coastal Engineering 1968, 1968
Collective movements of sediment occur in the form of sand waves m the nearshore zone and affect beach topography to a significant extent. Bar-type sand waves move only in the onshore direction and account for various accretive profiles on the subaerial beach.
openaire   +2 more sources