Results 61 to 70 of about 60,124 (259)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ciclos de movilización y crisis de derechos humanos. La acción colectiva de las ONGs nacionales y los derechos humanos en México

Revista de Estudios Sociales, 2016
This article is a contribution to studies of collective action and human rights mobilization. Two paradigmatic conjunctures in human rights advocacy in Mexico are analyzed and compared using the methodological proposal of cycles of mobilization, arguing ...
Sandra Hincapié Jiménez, Jairo Antonio López Pacheco   +1 more
doaj   +1 more source

Mandatory anti-SARS-CoV-2 vaccination: Seeking a balance between individual and collective rights. The Italian experience. [PDF]

Ethics Med Public Health, 2022
Franzetti C, Bolcato V.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Collective Biopolitic. The Rights of Indigenous Peoples in Genetic Research

Tecnoscienza, 2019
This essay considers issues implicated in biobanking with indigenous peoples, a population increasingly recognized as having a collective right to participation under international law (e.g., the United Nations Declaration on the Rights of Indigenous ...
Ibrahim Garba
doaj   +1 more source

Right to Asylum – the Collective Enforcement of Individual Right or Collective Right?

Societas et Iurisprudentia, 2018
Human rights protection and the right to asylum. New developments in the material sources of law – the current refugee and migration crisis in Europe. Collective transfer of persons from their homeland to the European Union. Considerations de lege ferenda – from the right to asylum perceived as an individual human right, to the right to asylum ...
openaire   +1 more source

The right to strike as a collective right of employees

XXI međunarodni naučni skup „Pravnički dani - Prof. dr Slavko Carić“, Odgovori pravne nauke na izazove savremenog društva - zbornik radova
Collective labor law, among other things, also includes instruments for solving collective labor disputes, such as: mediation, arbitration and strike as a last resort to fulfill the demands of employees. As one of the instruments for solving collective labor disputes, a strike is a collective interruption of the work of employees, which is organized ...
Sanja Škorić, Tamara Čičovački
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The guarantee of freedom of association and collective bargaining rights to domestic workers: two opposite models, Brazil and Canada

Pensar, 2017
The study’s main objective is to question the exclusion of domestic workers from freedom of association and collective bargaining rights and to propose possible policy solutions to allow the rights to these workers.
Ana Virgínia Moreira Gomes, Rupa Banerjee   +1 more
doaj   +1 more source