Results 31 to 40 of about 8,466,757 (309)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Collective route memories emerge through differential forgetting of navigational information in homing pigeons

open access: yesScientific Reports
Better decision-making in larger groups than smaller groups or individuals has been observed across various taxa. While this phenomenon is thought to result from the pooling of independent information in collective decision-making, an alternative ...
Joe Morford   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

RESEARCH METHOD FOR THE SOCIAL ACCEPTABILITY OF IMPLEMENTING A COLLECTIVE SYSTEM OF SEWAGE DISPOSAL AND TREATMENT

open access: yesEconomics and Environment, 2016
This article presents the procedure for assessing the social acceptability of the implementation of a collective sewage collection and treatment system, basing on the conditional valuation method, using the willingness to pay research (WTP).
Krystyna Rauba
doaj  

Levers to Improve Antibiotic Treatment of Lambs via Drinking Water in Sheep Fattening Houses: The Example of the Sulfadimethoxine/Trimethoprim Combination

open access: yesAntibiotics, 2020
To limit the spread of bacterial diseases in sheep fattening houses, antibiotics are often administered collectively. Collective treatments can be delivered by drinking water but data on the drug’s solubility in water or on plasma exposure of the animals
Aude A. Ferran   +4 more
doaj   +1 more source

FOR AN EFFICIENT TREATMENT OF EVIDENCE: THE MULTIDISTRICT LITIGATION AS A COLLECTIVE CASE MANAGEMENT TECHNIQUE

open access: yesRevista Eletrônica de Direito Processual, 2021
This article analyzes the multidistrict litigation of North American law as a way of providing an adequate treatment to causes that have similar issues of fact and that, therefore, admit joint evidential instruction.
Giulia Zanetti, Thaís Amoroso Paschoal
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The analysis of tariffs for collective sewage treatment services in the cities of the warmińsko-mazurskie voivodeship

open access: yesEconomics and Environment, 2018
The aim of the article is to analyze the tariffs for collective sewage disposal in the cities of the Warmińsko-Mazurskie Voivodeship in terms of the type of tariffs and compliance with the principle of elimination of cross-subsidization. On the basis of
Ewa Rauba
doaj  

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